Below are some key events in Nonlinear's history so you can see how we have evolved over the years. It's been an interesting, and at times a very exciting journey!
Nonlinear Dynamics, a Waters Company, releases Progenesis QI and Progenesis QI for proteomics with a public launch at Analytica 2014. These new products include new features whilst combining the functionality of two previously separate branded software products, Progenesis and TransOmics™ Informatics into one. This maintains the recognition of Progenesis as world-leading software for ‘omics data analysis and its support for all major instruments you may have now or in the future, including additional features specifically to support Waters customers.
Nonlinear expands its software development team with the recruitment of two new software engineers.
Nonlinear Dynamics becomes part of Waters Corporation. Nonlinear continue to operate from their headquarters in Newcastle on Tyne; developing, selling and supporting Progenesis LC-MS for proteomics and Progenesis CoMet for metabolomics/lipidomics. As part of the acquisition the sales and support of Progenesis SameSpots software for 2D gel electrophoresis image analysis are transferred to our sister company, TotalLab.
Nonlinear expands its customer support team with the recruitment of a new customer support coordinator.
Progenesis LC-MS v4.1 is released with automatic reference run selection then alignment of imported runs and alignment quality scores reported.
Progenesis CoMet v2.0 is launched to market with automatic deconvolution of compound ions, an integrated search tool and improvements to the workflow.
Nonlinear releases Progenesis ClearSpec which deisotopes and charge deconvolutes thousands of high-resolution MS/MS spectra in seconds. It has multiple uses including protein characterisation studies, increasing reliability and accuracy of peptide and protein database searches and helping researchers build high quality spectral libraries.
A new Omics research platform from Waters is launched, which is developed by Nonlinear Dynamics and powered by Progenesis. The Waters TransOmics™ Informatics for Proteomics and TransOmics™ Informatics for Metabolomics software launches were announced at the 60th ASMS Conference in Vancouver, Canada.
Progenesis CoMet v2.0 beta is released which includes compound ion deconvolution and improvements to the workflow.
Progenesis SameSpots version 4.5 is released which allows users to link protein search results to spot data and put their 2D analysis into biological context.
Nonlinear unveils version 4.0 of Progenesis LC-MS with an extended workflow for the quantification and identification of proteins which includes multivariate statistics.
Nonlinear releases Progenesis CoMet v1.0, a new product developed to measure the relative abundances of metabolites through the analysis of LC-MS.
Progenesis LC-MS v3.0 is released including a workflow to analyse fractionated samples, the ability to normalise based on a sub-set of known peptide ions, import results from Scaffold (Proteome Software) and exclude non-unique peptides from protein quantification.
Progenesis SameSpots v4.0 is released with a new experimental design option as well as additional features to help manage data quality. It's followed later in the year by v4.1, which incorporates the SpotCheck workflow for monitoring the reproducibility of gel running.
Progenesis LC-MS v2.6 is released, with enhanced support for quality control, greater integration with external hardware and data formats, and further enhancements to peak detection.
Nonlinear starts 2010 with a new look for the company and Progenesis product range and a new, improved website.
A new management team is appointed to drive forward the Phoretix and TotalLab product ranges which are developed and marketed by TotalLab Ltd - a company spun out of Nonlinear Dynamics.
Nonlinear releases new versions of the Progenesis range, developed to enable reproducible proteomics research - Progenesis LC-MS v2.0, Progenesis SameSpots v3.3 and Progenesis MALDI v1.2 are showcased at the Proteomic Forum, Berlin
Progenesis SameSpots v3.0 outperforms GE Healthcare's Decyder and Syngene's Dymension in study published in the Journal of Proteome Research
Nonlinear's headquarters relocates to brand new, high-specification offices in the centre of Newcastle-upon-Tyne
Release of Progenesis MALDI v1.0 for biomarker discovery using MALDI-TOF or SELDI analysis
Distribution agreement with GeneBio for the Phenyx MS identification platform
New OEM agreement with UVP, LLC for the SameSpots 2D image analysis software
Nonlinear enters the label-free, quantitative LC-MS analysis market with the launch of Progenesis LC-MS v1.0
Launch of the new 21 CFR part 11 module for the TotalLab 1D gel analysis range
Release of Progenesis SameSpots v3.0 - the 2D analysis software that enabled the HUPO Reproducibility Study
Nonlinear Dynamics create the Fixing Proteomics Campaign, a community effort with endorsement from key opinion leaders, supporting best practices to help proteomics deliver in the future
National Cancer Research Institute, Japan validate predictive biomarkers on a clinical scale using Nonlinear Dynamics' SameSpots technology
Nonlinear Dynamics appoint Dr. Paul Goulding as Distributor Manager to expand sales in the Far East
Hoefer, Inc. signs agreement with Nonlinear Dynamics to distribute the TotalLab range of image analysis solutions
Nonlinear Dynamics Enter Co-Marketing Agreement with Agilent
Nonlinear Dynamics' Progenesis SameSpots becomes fastest selling 2D software in the company history
Nonlinear Dynamics create Progenesis SameSpots, a new approach to 2D image analysis incorporating TT900 S2S
HUPO and Nonlinear launch the HUPO 5th Annual World Congress, Long Beach 2006 website
NE BioGroup to distribute TotalLab range throughout the US
Announce the release of the new 'Technologies' range, the first product, TT900 S2S is launched with immediate success - first copy licensed by the University of Newcastle upon Tyne
Nonlinear enters the Biomarker Discovery market with PG600
Invitrogen Corporation and Nonlinear sign distribution agreement
Enters co-development and co-marketing agreement with Waters Corporation
Nonlinear undertakes a global corporate re-brand and announces the launch of the new TotalLab TL and Progenesis PG range of products
Collaborates with The Human Proteome Organisation (HUPO) to develop and support their online activities
Extends OEM partnership with PerkinElmer to incorporate the full Nonlinear analysis range
Awarded the prestigious 'Product Line Innovation Award 2004' by Frost and Sullivan
Listed again in the Deloitte Fast 50 and Sunday Times Fast Track 100
Announce a third consecutive year of record turnover
Signs global OEM agreement with Shimadzu Corporation
Second year in top ten of Deloitte Fast 50 for the North, also ranked in Sunday Times Fast Track 100
Genomic Solutions signs OEM distribution agreement with Nonlinear Dynamics
Second year of record sales and further profits
Decides not to renew OEM contract with proteomics group at Amersham Biosciences
PerkinElmer, Inc signs new OEM distribution agreement
Releases Progenesis Discovery Informatics - University of Texas Medical Branch at Galveston immediate customer
Collaborates with Amersham Biosciences with exclusive software deal for ImageQuant TL
Extends range of software for 2D electrophoresis image analysis
Receives Exceptional SMART award and SMART Achievement Award
Expands Asian Pacific representation with new distributors and Asia Pacific General Manager
Collaborates with Amersham Biosciences to automate protein picking from bands in 1-D electrophoresis gels
PerkinElmer - OEM agreement for Progenesis
Amersham Pharmacia Biotech - OEM agreement for Progenesis
Expands US subsidiary
Releases Progenesis, unique Bioinformatics solution
Incorporation of US subsidiary, Nonlinear USA Inc.
Makes a profit for the fifth consecutive year
Releases multi-application analysis product, TotalLab
Receives fourth DTI-sponsored SMART award
Releases a new product range for the analysis of arrays
Accredited to ISO-9001 / TickIT
Receives "Outstanding Business Development" award
Signs OEM deal with Pharmacia Biotech to sell its products as "ImageMaster"
Releases 1D and 2D Database products
Increases turnover by 300%
First OEM deal, with Bio-Rad Laboratories Inc.
Releases first product for analysing 1D electrophoresis gels
Phoretix 2D first released to great acclaim
Will Dracup founds Nonlinear Dynamics