Waters | Nonlinear Dynamics

Progenesis QI for proteomics

The next generation in LC-MS proteomics data analysis software.
Discover the significantly changing proteins in your samples.

Download

How do I use the QC metrics precursor m/z chart?

This chart shows the distribution of your MS1 precursor m/z values, both identified and unidentified. Given the single aggregate codetection, this metric does not alter with experiment design – the value is based on the aggregate of runs.

Analogously to the Peptide ion dynamic range chart, this is a proportional distribution plot. Each bar represents the proportion of all peptide ions present that are within the binned m/z range. Identified peptide ions are marked in yellow to examine any correlation of m/z with successful identification.

The expected distribution shown on this chart is very much dependent on the m/z range optimised for your instrument and your identification strategy. Masking of regions in the detection may also affect the distribution of these values.

The (Overview) Precursor m/z chart.

The (Overview) Precursor m/z chart.

See also