Waters | Nonlinear Dynamics

Progenesis LC-MS

A unique approach for label-free LC-MS data analysis
Quantify and identify the significant proteins in your experiment…

Support for Bruker Daltonics .d folders

Download Bruker Daltonics .d folders

About this plug-in

This is the standard format produced by Bruker Daltonics mass spectrometers. Each sample run is contained within a separate .d folder, which typically contains a file named either analysis.baf or analysis.yep.

Before installing

To use this importer you will need CompassXtract 32Bit v3.1.2 or later. If you do not have this installed it can be downloaded after logging in on the Bruker Daltonics' website..

Usage

To select samples to import, first click the Browse button:

Selecting parent folder

Select the parent folder containing your .d folders and click OK.

The .d folders within the parent will then be shown in the Select samples list box:

Selecting samples

Select the samples you want to import and click Next to move on to the next step.

The next page allows you to include a linear m/z calibration as part of the import process:

m/z calibration

If you have included 2 calibrants of a known mass in your experimental samples, you can use these ions to calibrate the sample m/z values as they are imported. To do this, select Perform m/z calibration and set the expected m/z and charge for the calibrant ions. The other required option are:

  • Intensity threshold: the minimum intensity in counts for a calibrant peak to be used in calibration.
  • m/z window: the minimum m/z range over which the calibration algorithm should search for calibrant peaks.

If you do not want to apply an m/z calibration, clear the Perform m/z calibration checkbox.

Click the Import button to begin the data import.

See also