Waters | Nonlinear Dynamics

Progenesis LC-MS

A unique approach for label-free LC-MS data analysis
Quantify and identify the significant proteins in your experiment…

Supported search engines and databases

Mascot

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The Mascot search engine from Matrix Science allows identification of peptides, searching against multiple primary sequence databases including MSDB, NCBInr and SwissProt. This is an improved version of the Mascot identification loader which supports loading results from Error Tolerant searches.

To be able to load exported search results, the search should be performed using an MGF file created by Progenesis LC-MS.

To output the search results from Mascot:

  1. Select the Export Search Results option from the dropdown list alongside the Format As button
  2. Click the Format As button
    The Mascot search results page
  3. In the following page, select XML in the Export Format option
    Setting the export format as XML
  4. Make sure that Query title in the Peptide Match Information section is selected
    Making sure the query title is exported
  5. Click the Export Search Results button at the bottom of the page
Export format:Mascot generic format (*.mgf)
Import format:Mascot search results (*.xml)

See also

More peptide search formats supported by Progenesis LC-MS.