Nonlinear Dynamics: A Waters Company

UK: +44 191 230 2121
USA: +1 919 806 4401

"Everything about Nonlinear Dynamics makes it a great company to work with..."

Merry L. Lindsey
Ph.D., Assistant Professor
University of Texas Health Science Center at San Antonio

Nonlinear Overview

Nonlinear Dynamics develops next-generation LC-MS data analysis software under the Progenesis™ QI brand name for extracting fundamental information from omics data sets. Two leading products, Progenesis QI for small-molecule applications and Progenesis QI for proteomics applications, deliver highly-accurate quantitative data analysis with simplicity, scalability, statistical processing and improved visualizations.

1989 to present day

Nonlinear Dynamics, a private company founded in 1989, started life developing 1D and 2D gel analysis software. In 2008, it applied its established expertise in proteomics to move into LC-MS based data analysis with the launch of Progenesis LC-MS, a product that quickly gained wide recognition within the field for its unique “quantify and then identify” approach to the analysis of label-free LC-MS data. Expansion into the field of metabolomics soon followed, with the launch in 2011 of Progenesis CoMet, a product that incorporated and built upon the same strengths as its proteomics forebear.

An agreement was subsequently reached with Waters Corporation, who supplied the Progenesis software under its TransOmics™ Informatics name, delivering enhanced data analysis to support the functionality from Synapt-G2, Synapt-G2S and Synapt-G2Si high-definition mass-spectrometers. Ultimately, this successful arrangement led to Nonlinear being acquired by Waters in August 2013

Soon thereafter, the Progenesis and TransOmics™ Informatics were merged under the new Progenesis QI brand. This new software maintains the strengths of both parents — support for all major instrument vendors, plus enhanced analysis that makes the most of Waters' state-of-the-art mass spectrometry — and continues to go from strength to strength today.

Nonlinear's offices

Nonlinear is based in Newcastle upon Tyne, on the North East coast of England and has an office in Durham, North Carolina, USA supporting the Americas. Nonlinear maintain support for its customers with a dedicated customer care team which is renowned for its rapid response and expert advice.