To generate reliable reproducible results, which are relevant to biological populations or clinical applications, you need to run significant numbers of replicates in a realistic time, apply objective analysis and use the power of multivariate statistics with a complete data set. To generate results with this impact you need good experiment design and software specifically designed with these needs in mind. The Progenesis products have been developed to address these challenges.

Speed

Our unique alignment technology is at the core of all the products in the Progenesis range. Your data can be automatically and accurately aligned to provide geometrically corrected image data with no missing values. The subsequent detection and measurement of this aligned data is incredibly fast when compared to traditional analysis methods.

"Progenesis SameSpots has greatly reduced the time needed for 2D-DIGE analysis. I can now complete an analysis in less than one-quarter of the time that it would have taken when using the previous supplier's software, while at the same time obtaining more consistent and reliable results due to the excellent gel alignment and spot matching features."

Todd M. Umstead
Pennsylvania State University College of Medicine, US

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Objectivity

The guided workflow with automatic processes facilitates an objective analysis. It is possible to complete the full analysis with minimal input. Whilst there are tools to edit data in parts of the workflow, for example for the editing of detected features, these tools are developed to be as automated as possible so a different user will have minimal affect on the analysis results.

"Progenesis LC-MS offers a user friendly interface with logical and simple progression through the data analysis process. Each quantitative observation is accompanied with fantastic levels of statistical analysis which facilitates an unprecedented level of data understanding with minimal user input."

Dr Duncan Smith
Head of Biological Mass Spectrometry, Paterson Institute for Cancer Research, University of Manchester, UK

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Statistics

Multivariate statistical analysis is performed on a complete data set with no missing values. The statistical tools in this part of the workflow are exceptionally easy to use, with clear explanations to help the non-statistician. They help you identify the sources of variation in your data e.g. is it biological or technical, how closely related features are, report q-values and measure the power of your experiment for publication.

"The Progenesis LC-MS package has enabled our service lab customers to be taught in a very short time how to extract reliable results with they are happy. The interface is truly intuitive and the alignment accurate and the results analysis package enables them to perform the work without the need for a statistician."

Peter James
Prof. of Protein Technology, Lund University, Sweden

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Looking for software for 1D gels, blots, arrays, and colonies?

Try www.totallab.com:

• For 1D gel and blot analysis, see Phoretix 1D and 1D Pro
• For Array analysis, see Phoretix Array Pro
• For easy, automated analysis, see TotalLab Quant
• For GxP and 21 CFR Part 11, see Phoretix 1D 21CFR