Progenesis QI software references

2019

Alldritt I, Whitham-Agut B, Sipin M, Studholme J, Trentacoste A, Tripp JA, Cappai MG, Ditchfield P, Deviese T, Hedges REM, McCullagh JSO (2019) Metabolomics reveals diet-derived plant polyphenols accumulate in physiological bone. Sci Rep 9:8047

Anzmann AF, Pinto S, Busa V, Carlson J, McRitchie S, Sumner S, Pandey A, Vernon HJ (2019) Multi-omics studies in cellular models of methylmalonic acidemia and propionic acidemia reveal dysregulation of serine metabolism. Biochim Biophys Acta Mol Basis Dis 1865:165538

Ao Z, Li Z, Wang X, Zhao C, Gan Y, Wu X, Zeng F, Shi J, Gu T, Hong L, Zheng E, Liu D, Xu Z, Wu Z, Cai G (2019) Identification of amniotic fluid metabolomic and placental transcriptomic changes associated with abnormal development of cloned pig fetuses. Mol Reprod Dev 86:278-291

Ao Z, Wu X, Zhou J, Gu T, Wang X, Shi J, Zhao C, Cai G, Zheng E, Liu D, Wu Z, Li Z (2019) Cloned pig fetuses exhibit fatty acid deficiency from impaired placental transport. Mol Reprod Dev 86:1569-1581

Arndt D, Wachsmuth C, Buchholz C, Bentley M (2019) A complex matrix characterization approach, applied to cigarette smoke, that integrates multiple analytical methods and compound identification strategies for non-targeted liquid chromatography with high-resolution mass spectrometry. Rapid Commun Mass Spectrom (in press)

Artegoitia VM, Foote AP, Lewis RM, Freetly HC (2109) Metabolomics Profile and Targeted Lipidomics in Multiple Tissues Associated with Feed Efficiency in Beef Steers. ACS Omega 4:3973-3982

Bai Y, Zhao Q, He M, Ye X, Zhang X (2019) Extensive characterization and differential analysis of endogenous peptides from Bombyx batryticatus using mass spectrometric approach. J Pharm Biomed Anal 163:78-87

Barros Santos MC, Ribeiro da Silva Lima L, Ramos Nascimento F, Pimenta do Nascimento T, Cameron LC, Simoes Larraz Ferreira M (2019) Metabolomic approach for characterization of phenolic compounds in different wheat genotypes during grain development. Food Res Int 124:118-128

Bell M, Blais JM (2019) "-Omics" workflow for paleolimnological and geological archives: A review. Sci Total Environ 672:438-455

Bharucha T, Gangadharan B, Kumar A, de Lamballerie X, Newton PN, Winterberg M, Dubot-Peres A, Zitzmann N (2019) Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review. J Infect 79:407-418

Brehm L, Frank O, Junger M, Wimmer M, Ranner J, Hofmann T (2019) Novel Taste-Enhancing 4-Amino-2-methyl-5-heteroalkypyrimidines Formed from Thiamine by Maillard-Type Reactions. J Agric Food Chem 67:13986-13997

Brown EM, Ke X, Hitchcock D, Jeanfavre S, Avila-Pacheco J, Nakata T, Arthur TD, Fornelos N, Heim C, Franzosa EA, Watson N, Huttenhower C, Haiser HJ, Dillow G, Graham DB, Finlay BB, Kostic AD, Porter JA, Vlamakis H, Clish CB, Xavier RJ (2019) Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis. Cell Host Microbe 25:668-680 e667

Bunning BJ, Contrepois K, Lee-McMullen B, Dhondalay GKR, Zhang W, Tupa D, Raeber O, Desai M, Nadeau KC, Snyder MP, Andorf S (2019) Global metabolic profiling to model biological processes of aging in twins. Aging Cell:e13073

Cai X, Liang N, Wang H, Gao A, Xiao R, Yu H (2019) Lipidomic profiles of maternal blood at the earlier stage of gestation and umbilical venous blood in response to supraphysiological hypercholesterolemia versus physiological hypercholesterolemia: An evidence of potential biomarkers and early intervention. Biochim Biophys Acta Mol Cell Biol Lipids:158587

Chaffin MD, Cao L, Deik AA, Clish CB, Hu FB, Martinez-Gonzalez MA, Razquin C, Bullo M, Corella D, Gomez-Gracia E, Fiol M, Estruch R, Lapetra J, Fito M, Aros F, Serra-Majem L, Ros E, Liang L (2019) MetProc: Separating Measurement Artifacts from True Metabolites in an Untargeted Metabolomics Experiment. J Proteome Res 18:1446-1450

Chakrabarti P, Morre JT, Lucas HM, Maier CS, Sagili RR (2019) The omics approach to bee nutritional landscape. Metabolomics 15:127

Chan LY, Takahashi M, Lim PJ, Aoyama S, Makino S, Ferdinandus F, Ng SYC, Arai S, Fujita H, Tan HC, Shibata S, Lee CK (2019) Eurotium Cristatum Fermented Okara as a Potential Food Ingredient to Combat Diabetes. Sci Rep 9:17536

Chatterjee NS, Chevallier OP, Wielogorska E, Black C, Elliott CT (2019) Simultaneous authentication of species identity and geographical origin of shrimps: Untargeted metabolomics to recurrent biomarker ions. J Chromatogr A 1599:75-84

Chen C, Li H, Niu Y, Liu C, Lin Z, Cai J, Li W, Ge W, Chen R, Kan H (2019) Impact of short-term exposure to fine particulate matter air pollution on urinary metabolome: A randomized, double-blind, crossover trial. Environ Int 130:104878

Chen H, Nie Q, Hu J, Huang X, Zhang K, Nie S (2019) Glucomannans Alleviated the Progression of Diabetic Kidney Disease by Improving Kidney Metabolic Disturbance. Mol Nutr Food Res 63:e1801008

Cheng M, Wu H, Liu X, Zhou A (2019) Metabolic profiling of copper-laden hepatolenticular degeneration model rats and the interventional effects of Gandou decoction using UPLC-Q-TOF/MS. J Pharm Biomed Anal 164:187-195

Cheng ML, Lin JF, Huang CY, Li GJ, Shih LM, Chiu DT, Ho HY (2019) Sedoheptulose-1,7-bisphospate Accumulation and Metabolic Anomalies in Hepatoma Cells Exposed to Oxidative Stress. Oxid Med Cell Longev 2019:5913635

Claassen C, Ebel E, Kuballa J, Rohn S (2019) Impacts of Fungicide Treatment and Conventional Fertilization Management on the Potato Metabolome (Solanum tuberosum L.) Evaluated with UPLC-IMS-QToF. J Agric Food Chem 67:11542-11552

Claassen C, Kuballa J, Rohn S (2019) Metabolomics-Based Approach for the Discrimination of Potato Varieties ( Solanum tuberosum) using UPLC-IMS-QToF. J Agric Food Chem 67:5700-5709

Clendinen CS, Gaul DA, Monge ME, Arnold RS, Edison AS, Petros JA, Fernandez FM (2019) Preoperative Metabolic Signatures of Prostate Cancer Recurrence Following Radical Prostatectomy. J Proteome Res 18:1316-1327

Commisso M, Negri S, Bianconi M, Gambini S, Avesani S, Ceoldo S, Avesani L, Guzzo F (2019) Untargeted and Targeted Metabolomics and Tryptophan Decarboxylase In Vivo Characterization Provide Novel Insight on the Development of Kiwifruits (Actinidia deliciosa). Int J Mol Sci 20 (in press)

Contessotto P, Ellis BW, Jin C, Karlsson NG, Zorlutuna P, Kilcoyne M, Pandit A (2019) Distinct glycosylation in membrane proteins within neonatal versus adult myocardial tissue. Matrix Biol (in press)

Cozma C, Hovakimyan M, Iurascu MI, Makhseed N, Selim LA, Alhashem AM, Ben-Omran T, Mahmoud IG, Al Menabawy NM, Al-Mureikhi M, Martin M, Demuth L, Yuksel Z, Beetz C, Bauer P, Rolfs A (2019) Genetic, clinical and biochemical characterization of a large cohort of patients with hyaline fibromatosis syndrome. Orphanet J Rare Dis 14:209

Cui L, Wang X, Sun B, Xia T, Hu S (2019) Predictive Metabolomic Signatures for Safety Assessment of Metal Oxide Nanoparticles. ACS Nano 13:13065-13082

Dai Y, Jin R, Verpoorte R, Lam W, Cheng YC, Xiao Y, Xu J, Zhang L, Qin XM, Chen S (2019) Natural deep eutectic characteristics of honey improve the bioactivity and safety of traditional medicines. J Ethnopharmacol:112460

Dickinson E, Harrison M, Parker M, Dickinson M, Donarski J, Charlton A, Nolan R, Rafat A, Gschwend F, Hallett J, Wakefield M, Wilson J (2019) From waste to food: Optimising the breakdown of oil palm waste to provide substrate for insects farmed as animal feed. PLoS One 14:e0224771

Ding K, Zhang L, Zhang T, Yang H, Brinkman R (2019) The Effect of Melatonin on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus. Front Physiol 10:221

Dionisio G, Gautam M, Fomsgaard IS (2019) Identification of Azoxystrobin Glutathione Conjugate Metabolites in Maize Roots by LC-MS. Molecules 24 (in press)

do Nascimento TP, Santos MCB, de Abreu JP, de Almeida I, Feijo M, Teodoro AJ, Ferreira MSL, Cameron LC, Koblitz MGB (2019) Effects of cooking on the phytochemical profile of breadfruit as revealed by high-resolution UPLC-MS(E). J Sci Food Agric (in press)

Du WZ, Zhang AH, Ren JL, Lyu K, Tuo LY, Xu W (2019) Study of Differential Serum Metabolites in Patients with Adenomatous Polyps of Colon and Yang-Deficiency Constitution Based on Ultra-performance Liquid Chromatography-Mass Spectrometry. Chin J Integr Med (in press)

Du Y, Hou L, Chu C, Jin Y, Sun W, Zhang R (2019) Characterization of serum metabolites as biomarkers of carbon black nanoparticles-induced subchronic toxicity in rats by hybrid triple quadrupole time-of-flight mass spectrometry with non-targeted metabolomics strategy. Toxicology 426:152268

Eberly AR, Beebout CJ, Carmen Tong CM, Van Horn GT, Green HD, Fitzgerald MJ, De S, Apple EK, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Clayton DB, Stratton CW, Schmitz JE, Hadjifrangiskou M (2019) Defining a Molecular Signature for Uropathogenic versus Urocolonizing Escherichia coli: The Status of the Field and New Clinical Opportunities. J Mol Biol (in press)

Eisenbeiss L, Steuer AE, Binz TM, Baumgartner MR, Kraemer T (2019) (Un)targeted hair metabolomics: first considerations and systematic evaluation on the impact of sample preparation. Anal Bioanal Chem(in press)

El Banna N, Hatem E, Heneman-Masurel A, Leger T, Baille D, Vernis L, Garcia C, Martineau S, Dupuy C, Vagner S, Camadro JM, Huang ME (2019) Redox modifications of cysteine-containing proteins, cell cycle arrest and translation inhibition: Involvement in vitamin C-induced breast cancer cell death. Redox Biol 26:101290

Ellis BM, Fischer CN, Martin LB, Bachmann BO, McLean JA (2019) Spatiochemically Profiling Microbial Interactions with Membrane Scaffolded Desorption Electrospray Ionization-Ion Mobility-Imaging Mass Spectrometry and Unsupervised Segmentation. Anal Chem 91:13703-13711

Fader KA, Nault R, Doskey CM, Fling RR, Zacharewski TR (2019) 2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice. Sci Rep 9:6514

Fan M, Fan Y, Rao Z, Li Y, Qian H, Zhang H, Wu G, Qi X, Wang L (2019) Comparative investigation on metabolite changes in 'wu mi' production by Vaccinium bracteatum Thunb. leaves based on multivariate data analysis using UPLC-QToF-MS. Food Chem 286:146-153

Fang H, Zhang AH, Sun H, Yu JB, Wang L, Wang XJ (2019) High-throughput metabolomics screen coupled with multivariate statistical analysis identifies therapeutic targets in alcoholic liver disease rats using liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 1109:112-120

Fasciotti M, Souza G, Astarita G, Costa ICR, Monteiro TVC, Teixeira C, Eberlin MN, Sarpal AS (2019) Investigating the potential of ion mobility-mass spectrometry for microalgae biomass characterization. Anal Chem (in press)

Feng Z, Hou J, Yu Y, Wu W, Deng Y, Wang X, Zhi H, Zhang L, Guo DA (2019) Dissecting the Metabolic Phenotype of the Antihypertensive Effects of Five Uncaria Species on Spontaneously Hypertensive Rats. Front Pharmacol 10:845

Fennell TR, Watson SL, Dhungana S, Snyder RW (2019) Metabolism of 4-methylimidazole in Fischer 344 rats and B6C3F1 mice. Food Chem Toxicol 123:181-194

Finelli MJ, Paramo T, Pires E, Ryan BJ, Wade-Martins R, Biggin PC, McCullagh J, Oliver PL (2019) Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase. Mol Neurobiol 56:1558-1577

Freiburghaus K, Largiader CR, Stettler C, Fiedler GM, Bally L, Bovet C (2019) Metabolomics by UHPLC-MS: benefits provided by complementary use of Q-TOF and QQQ for pathway profiling. Metabolomics 15:120

Gagnebin Y, Pezzatti J, Lescuyer P, Boccard J, Ponte B, Rudaz S (2019) Toward a better understanding of chronic kidney disease with complementary chromatographic methods hyphenated with mass spectrometry for improved polar metabolome coverage. J Chromatogr B Analyt Technol Biomed Life Sci 1116:9-18

Galle-Treger L, Hurrell BP, Lewis G, Howard E, Jahani PS, Banie H, Razani B, Soroosh P, Akbari O (2019) Autophagy is critical for group 2 innate lymphoid cell metabolic homeostasis and effector function. J Allergy Clin Immunol (in press)

Gao J, Huang T, Li J, Guo X, Xiao H, Gu J, Tang J, Cai W, Li D (2019) Beneficial Effects of n-3 Polyunsaturated Fatty Acids on Offspring's Pancreas of Gestational Diabetes Rats. J Agric Food Chem 67:13269-13281

Gao S, Wan Y, Li W, Huang C (2019) Visualized Networking of Co-Regulated Lipids in Human Blood Based on High-Throughput Screening Data: Implications for Exposure Assessment. Environ Sci Technol 53:2862-2872

Gao X, Hu X, Zhang Q, Wang X, Wen X, Wang Y, Zhang Y, Sun W (2019) Characterization of chemical constituents and absorbed components, screening the active components of gelanxinning capsule and an evaluation of therapeutic effects by ultra-high performance liquid chromatography with quadrupole time of flight mass spectrometry. J Sep Sci 42:3439-3450

Gao Y, Wang Z, Tang J, Liu X, Shi W, Qin N, Wang X, Pang Y, Li R, Zhang Y, Wang J, Niu M, Bai Z, Xiao X (2019) New incompatible pair of TCM: Epimedii Folium combined with Psoraleae Fructus induces idiosyncratic hepatotoxicity under immunological stress conditions. Front Med (in press)

Garcia-Jaramillo M, Spooner MH, Lohr CV, Wong CP, Zhang W, Jump DB (2019) Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice. PLoS One 14:e0214387

Garran TA, Ji R, Chen JL, Xie D, Guo L, Huang LQ, Lai CJ (2019) Elucidation of metabolite isomers of Leonurus japonicus and Leonurus cardiaca using discriminating metabolite isomerism strategy based on ultra-high performance liquid chromatography tandem quadrupole time-of-flight mass spectrometry. J Chromatogr A 1598:141-153

Ge G, Jiao W, Cui C, Liao G, Sun J, Hou R (2019) Thiamethoxam metabolism and metabolic effects in cell suspension culture of tea (Camellia sinensis L.). J Agric Food Chem (in press)

Gobert AP, Latour YL, Asim M, Finley JL, Verriere TG, Barry DP, Milne GL, Luis PB, Schneider C, Rivera ES, Lindsey-Rose K, Schey KL, Delgado AG, Sierra JC, Piazuelo MB, Wilson KT (2019) Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway. MBio 10 (in press)

Gong LL, Yang S, Zhang W, Han FF, Lv YL, Xuan LL, Liu H, Liu LH (2019) Discovery of metabolite profiles of metabolic syndrome using untargeted and targeted LC-MS based lipidomics approach. J Pharm Biomed Anal 177:112848

Gooding J, Cao L, Whitaker C, Mwiza JM, Fernander M, Ahmed F, Acuff Z, McRitchie S, Sumner S, Ongeri EM (2019) Meprin beta metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy. BMC Nephrol 20:141

Gorrochategui E, Jaumot J, Tauler R (2019) ROIMCR: a powerful analysis strategy for LC-MS metabolomic datasets. BMC Bioinformatics 20:256

Gu R, Rybalov L, Negrin A, Morcol T, Long W, Myers AK, Isaac G, Yuk J, Kennelly EJ, Long C (2019) Metabolic Profiling of Different Parts of Acer truncatum from the Mongolian Plateau Using UPLC-QTOF-MS with Comparative Bioactivity Assays. J Agric Food Chem 67:1585-1597

Guan Q, Ding XW, Jiang R, Ouyang PL, Gui J, Feng L, Yang L, Song LH (2019) Effects of hydrogen-rich water on the nutrient composition and antioxidative characteristics of sprouted black barley. Food Chem 299:125095

Guan S, Jia B, Chao K, Zhu X, Tang J, Li M, Wu L, Xing L, Liu K, Zhang L, Wang X, Gao X, Huang M (2019) UPLC- QTOF - MS Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis. J Proteome Res (in press)

Guo C, Baluya DL, Thompson EA, Whitley EM, Cressman ENK (2019) Correlation of molecular and morphologic effects of thermoembolization in a swine model using mass spectrometry imaging. J Mass Spectrom (in press)

Guo XH, Cheng XL, Liu WX, Li MH, Wei F, Ma SC (2019) Identification of velvet antler and its mixed varieties by UPLC-QTOF-MS combined with principal component analysis. J Pharm Biomed Anal 165:18-23

Guo Y, Yu H, Chen D, Zhao YY (2019) Machine learning distilled metabolite biomarkers for early stage renal injury. Metabolomics 16:4

Hammerl R, Frank O, Schmittnagel T, Ehrmann MA, Hofmann T (2019) Functional Metabolome Analysis of Penicillium roqueforti by Means of Differential Off-Line LC-NMR. J Agric Food Chem 67:5135-5146

Hao L, Zhu Y, Wei P, Johnson J, Buchberger A, Frost D, Kao WJ, Li L (2019) Metandem: An online software tool for mass spectrometry-based isobaric labeling metabolomics. Anal Chim Acta 1088:99-106

He M, Gao J, Wu J, Zhou Y, Fu H, Ke S, Yang H, Chen C, Huang L (2019) Host Gender and Androgen Levels Regulate Gut Bacterial Taxa in Pigs Leading to Sex-Biased Serum Metabolite Profiles. Front Microbiol 10:1359

Hernandez-Alonso P, Papandreou C, Bullo M, Ruiz-Canela M, Dennis C, Deik A, Wang DD, Guasch-Ferre M, Yu E, Toledo E, Razquin C, Corella D, Estruch R, Ros E, Fito M, Aros F, Fiol M, Serra-Majem L, Liang L, Clish CB, Martinez-Gonzalez MA, Hu FB, Salas-Salvado J (2019) Plasma Metabolites Associated with Frequent Red Wine Consumption: A Metabolomics Approach within the PREDIMED Study. Mol Nutr Food Res 63:e1900140

Herrera MD, Acosta-Gallegos JA, Reynoso-Camacho R, Perez-Ramirez IF (2019) Common bean seeds from plants subjected to severe drought, restricted- and full-irrigation regimes show differential phytochemical fingerprint. Food Chem 294:368-377

Hines KM, Xu L (2019) Lipidomic consequences of phospholipid synthesis defects in Escherichia coli revealed by HILIC-ion mobility-mass spectrometry. Chem Phys Lipids 219:15-22

Hoffmann N, Rein J, Sachsenberg T, Hartler J, Haug K, Mayer G, Alka O, Dayalan S, Pearce JTM, Rocca-Serra P, Qi D, Eisenacher M, Perez-Riverol Y, Vizcaino JA, Salek RM, Neumann S, Jones AR (2019) mzTab-M: A Data Standard for Sharing Quantitative Results in Mass Spectrometry Metabolomics. Anal Chem 91:3302-3310

Hsu JF, Tien CP, Shih CL, Liao PM, Wong HI, Liao PC (2019) Using a high-resolution mass spectrometry-based metabolomics strategy for comprehensively screening and identifying biomarkers of phthalate exposure: Method development and application. Environ Int 128:261-270

Hua YL, Ma Q, Li W, Zhang XS, Cheng XH, Jia YQ, Peng XT, Yao WL, Ji P, Hu JJ, Wei YM (2019) Metabolomics analysis of Pulsatilla decoction on treatment of wetness-heat-induced diarrhea in rats based on UPLC-Q/TOF-MS/MS. Biomed Chromatogr 33:e4629

Huang W, Gfeller V, Erb M (2019) Root volatiles in plant-plant interactions II: Root volatiles alter root chemistry and plant-herbivore interactions of neighbouring plants. Plant Cell Environ 42:1964-1973

Huang X, Gao J, Zhao Y, He M, Ke S, Wu J, Zhou Y, Fu H, Yang H, Chen C, Huang L (2019) Dramatic Remodeling of the Gut Microbiome Around Parturition and Its Relationship With Host Serum Metabolic Changes in Sows. Front Microbiol 10:2123

Huynh K, Reinhold D (2019) Metabolism of Sulfamethoxazole by the Model Plant Arabidopsis thaliana. Environ Sci Technol 53:4901-4911

Jang HR, Park HJ, Kang D, Chung H, Nam MH, Lee Y, Park JH, Lee HY (2019) A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption. Exp Mol Med 51:95

Jia C, Wei Y, Lan Y, Hou X, Zuo J, Wang T, Li J, Guan X, Yang H, Mao G (2019) Comprehensive analysis of the metabolomic characteristics on the health lesions induced by chronic arsenic exposure: A metabolomics study. Int J Hyg Environ Health 222:434-445

Jia Y, Zhou M, Huang H, Gan Y, Yang M, Ding R (2019) Characterization of circadian human facial surface lipid composition. Exp Dermatol 28:858-862

Jiang Y, Sun A, Zhao Y, Ying W, Sun H, Yang X, Xing B, et al. (2019) Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma. Nature 567:257-261

Jones JW, Sarkar C, Lipinski MM, Kane MA (2019) Detection and Structural Characterization of Ether Glycerophosphoethanolamine from Cortical Lysosomes Following Traumatic Brain Injury Using UPLC-HDMS(E). Proteomics:e1800297

Khan MSS, Basnet R, Islam SA, Shu Q (2019) Mutational Analysis of OsPLDalpha1 Reveals Its Involvement in Phytic Acid Biosynthesis in Rice Grains. J Agric Food Chem 67:11436-11443

King A, Baginski M, Morikawa Y, Rainville PD, Gethings LA, Wilson ID, Plumb RS (2019) Application of a Novel Mass Spectral Data Acquisition Approach to Lipidomic Analysis of Liver Extracts from Sitaxentan-Treated Liver-Humanized PXB Mice. J Proteome Res 18:4055-4064

King AM, Mullin LG, Wilson ID, Coen M, Rainville PD, Plumb RS, Gethings LA, Maker G, Trengove R (2019) Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC-MS and ion mobility enabled HILIC-MS. Metabolomics 15:17

King AM, Trengove RD, Mullin LG, Rainville PD, Isaac G, Plumb RS, Gethings LA, Wilson ID (2019) Rapid profiling method for the analysis of lipids in human plasma using ion mobility enabled-reversed phase-ultra high performance liquid chromatography/mass spectrometry. J Chromatogr A:460597

Knobloch TJ, Ryan NM, Bruschweiler-Li L, Wang C, Bernier MC, Somogyi A, Yan PS, Cooperstone JL, Mo X, Bruschweiler RP, Weghorst CM, Oghumu S (2019) Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention. Metabolites 9 (in press)

Kumar V, A AK, Sanawar R, Jaleel A, Santhosh Kumar TR, Kartha CC (2019) Chronic Pressure Overload Results in Deficiency of Mitochondrial Membrane Transporter ABCB7 Which Contributes to Iron Overload, Mitochondrial Dysfunction, Metabolic Shift and Worsens Cardiac Function. Sci Rep 9:13170

Kumar V, Kumar AA, Joseph V, Dan VM, Jaleel A, Kumar TRS, Kartha CC (2019) Untargeted metabolomics reveals alterations in metabolites of lipid metabolism and immune pathways in the serum of rats after long-term oral administration of Amalaki rasayana. Mol Cell Biochem (in press)

Laiakis EC, Canadell MP, Grilj V, Harken AD, Garty GY, Astarita G, Brenner DJ, Smilenov L, Fornace AJ, Jr. (2019) Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype. Sci Rep 9:4539

Laiakis EC, Nishita D, Bujold K, Jayatilake MM, Bakke J, Gahagen J, Authier S, Chang P, Fornace AJ, Jr. (2019) Salivary Metabolomics of Total Body Irradiated Nonhuman Primates Reveals Long-Term Normal Tissue Responses to Radiation. Int J Radiat Oncol Biol Phys 105:843-851

Lazzaro S, Ogrinc N, Lamont L, Vecchio G, Pappalardo G, Heeren RMA (2019) Ion mobility spectrometry combined with multivariate statistical analysis: revealing the effects of a drug candidate for Alzheimer's disease on Abeta1-40 peptide early assembly. Anal Bioanal Chem 411:6353-6363

Li F, Xiang B, Jin Y, Li C, Li J, Ren S, Huang H, Luo Q (2019) Dysregulation of lipid metabolism induced by airway exposure to polycyclic aromatic hydrocarbons in C57BL/6 mice. Environ Pollut 245:986-993

Li F, Xiang B, Jin Y, Li C, Ren S, Wu Y, Li J, Luo Q (2019) Hepatotoxic effects of inhalation exposure to polycyclic aromatic hydrocarbons on lipid metabolism of C57BL/6 mice. Environ Int 134:105000

Li G, Zhang N, Geng F, Liu G, Liu B, Lei X, Chen X (2019) High-throughput metabolomics and ingenuity pathway approach reveals the pharmacological effect and targets of Ginsenoside Rg1 in Alzheimer's disease mice. Sci Rep 9:7040

Li H, Bullock K, Gurjao C, Braun D, Shukla SA, Bosse D, Lalani AA, Gopal S, Jin C, Horak C, Wind-Rotolo M, Signoretti S, McDermott DF, Freeman GJ, Van Allen EM, Schreiber SL, Stephen Hodi F, Sellers WR, Garraway LA, Clish CB, Choueiri TK, Giannakis M (2019) Metabolomic adaptations and correlates of survival to immune checkpoint blockade. Nat Commun 10:4346

Li H, Wang Y, Meng Q, Xia G, Xia X, Shen J (2019) Comprehensive proteomic and metabolomic profiling of mcr-1-mediated colistin resistance in Escherichia coli. Int J Antimicrob Agents 53:795-804

Li L, Fu WW, Wu RT, Song YH, Wu WY, Yin SH, Li WJ, Xie MY (2019) Protective effect of Ganoderma atrum polysaccharides in acute lung injury rats and its metabolomics. Int J Biol Macromol (in press)

Li P, Liu S, Liu Q, Shen J, Yang R, Jiang B, He C, Xiao P (2019) Screening of acetylcholinesterase inhibitors and characterizing of phytochemical constituents from Dichocarpum auriculatum (Franch.) W.T. Wang & P. K. Hsiao through UPLC-MS combined with an acetylcholinesterase inhibition assay in vitro. J Ethnopharmacol 245:112185

Li P, Oyang X, Xie X, Li Z, Yang H, Xi J, Guo Y, Tian X, Liu B, Li J, Xiao Z (2019) Phytotoxicity induced by perfluorooctanoic acid and perfluorooctane sulfonate via metabolomics. J Hazard Mater:121852

Li X, Liang Z, Du J, Wang Z, Mei S, Li Z, Zhao Y, Zhao D, Ma Y, Ye J, Xu J, Chang J, Qin Y, Yu L, Wang C, Jiang C (2019) Herbal decoctosome is a novel form of medicine. Sci China Life Sci 62:333-348

Li Y, Jones JW, H MCC, Sarkar C, Kane MA, Koh EY, Lipinski MM, Wu J (2019) cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury. Cell Death Dis 10:531

Li YY, Stewart DA, Ye XM, Yin LH, Pathmasiri WW, McRitchie SL, Fennell TR, Cheung HY, Sumner SJ (2019) A Metabolomics Approach to Investigate Kukoamine B-A Potent Natural Product With Anti-diabetic Properties. Front Pharmacol 9:1575

Lin YC, Huang C, Huang HC, Liao MT, Lai YH (2019) Metabolomics profiling of haloperidol and validation of thromboxane-related signaling in the early development of zebrafish. Biochem Biophys Res Commun 513:608-615

Liu FJ, Jiang Y, Li P, Liu YD, Yao ZP, Xin GZ, Li HJ (2019) Untargeted metabolomics coupled with chemometric analysis reveals species-specific steroidal alkaloids for the authentication of medicinal Fritillariae Bulbus and relevant products. J Chromatogr A:460630

Liu H, Chen X, Hu X, Niu H, Tian R, Wang H, Pang H, Jiang L, Qiu B, Zhang Y, Ma Y, Tang S, Li H, Feng S, Zhang S, Zhang C (2019) Alterations in the gut microbiome and metabolism with coronary artery disease severity. Microbiome 7:68

Liu H, Gu R, Li W, Zhou W, Cong Z, Xue J, Liu Y, Wei Q, Zhou Y (2019) Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation. Ther Adv Chronic Dis 10:2040622319860653

Liu L, Yin TL, Chen Y, Li Y, Yin L, Ding J, Yang J, Feng HL (2019) Follicular dynamics of glycerophospholipid and sphingolipid metabolisms in polycystic ovary syndrome patients. J Steroid Biochem Mol Biol 185:142-149

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Zhang AH, Ma ZM, Sun H, Zhang Y, Liu JH, Wu FF, Wang XJ (2019) High-Throughput Metabolomics Evaluate the Efficacy of Total Lignans From Acanthophanax Senticosus Stem Against Ovariectomized Osteoporosis Rat. Front Pharmacol 10:553

Zhang B, Li MY, Luo XM, Wang XB, Wu T (2019) Analysis of the chemical components of Qixianqingming granules and their metabolites in rats by UPLC-ESI-Q-TOF-MS. J Mass Spectrom (in press)

Zhang B, Sztojka B, Escamez S, Vanholme R, Hedenstrom M, Wang Y, Gorzsas A, Boerjan W, Tuominen H (2019) PIRIN2 suppresses S-type lignin accumulation in a noncell-autonomous manner in Arabidopsis xylem elements. New Phytol (in press)

Zhang G, Wang H, Xie W, Wang Q, Wang X, Wang C, Du Y, Huo C (2019) Comparison of triterpene compounds of four botanical parts from Poria cocos (Schw.) wolf using simultaneous qualitative and quantitative method and metabolomics approach. Food Res Int 121:666-677

Zhang H, Jiang JM, Zheng D, Yuan M, Wang ZY, Zhang HM, Zheng CW, Xiao LB, Xu HX (2019) A multidimensional analytical approach based on time-decoupled online comprehensive two-dimensional liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry for the analysis of ginsenosides from white and red ginsengs. J Pharm Biomed Anal 163:24-33

Zhang J, Wang X, Shi X, Xie J, Zhang M, Ma J, Wang F, Tang X (2019) Combination of 15 lipid metabolites and motilin to diagnose spleen-deficiency FD. Chin Med 14:16

Zhang M, Liu X, Li H, Sun W, Zhang Y (2019) A pilot investigation of a urinary metabolic biomarker discovery in renal cell carcinoma. Int Urol Nephrol (in press)

Zhang P, Gong Y, Liu Z, Liu Y, Lin W, Li J, Wang M, Liu X, Fei Y, Chen H, Peng L, Zhou J, Shi Q, Zhang X, Shen M, Zeng X, Zhang F, Li Y, Zhao Y, Zhang W (2019) Efficacy and safety of iguratimod plus corticosteroid as bridge therapy in treating mild IgG4-related diseases: A prospective clinical trial. Int J Rheum Dis 22:1479-1488

Zhang S, Nie L, Zhao W, Cui Q, Wang J, Duan Y, Ge C (2019) Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants. PLoS One 14:e0223707

Zhang X, Wang Y, Li S, Dai Y, Li X, Wang Q, Wang G, Ma Y, Gu X, Zhang C (2019) The Potential Antipyretic Mechanism of Gardeniae Fructus and Its Heat-Processed Products With Plasma Metabolomics Using Rats With Yeast-Induced Fever. Front Pharmacol 10:491

Zhang X, Wang Y, Li X, Dai Y, Wang Q, Wang G, Liu D, Gu X, Yu D, Ma Y, Zhang C (2019) Treatment Mechanism of Gardeniae Fructus and Its Carbonized Product Against Ethanol-Induced Gastric Lesions in Rats. Front Pharmacol 10:750

Zhang Y, Chu M, Zhang J, Duan J, Hu D, Zhang W, Yang X, Jia X, Deng F, Sun Z (2019) Urine metabolites associated with cardiovascular effects from exposure of size-fractioned particulate matter in a subway environment: A randomized crossover study. Environ Int 130:104920

Zhao Q, Gao X, Yan G, Zhang A, Sun H, Han Y, Li W, Liu L, Wang X (2019) Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency syndrome. Front Med (in press)

Zhao Q, Zhao N, Ye X, He M, Yang Y, Gao H, Zhang X (2019) Rapid discrimination between red and white ginseng based on unique mass-spectrometric features. J Pharm Biomed Anal 164:202-210

Zheng WB, Zou Y, Elsheikha HM, Liu GH, Hu MH, Wang SL, Zhu XQ (2019) Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis. Parasit Vectors 12:447

Zhou H, Li Q, Wang T, Liang H, Wang Y, Duan Y, Song M, Jin H (2019) Prognostic biomarkers of cervical squamous cell carcinoma identified via plasma metabolomics. Medicine (Baltimore) 98:e16192

Zhou J, Gu X, Fan X, Zhou Y, Wang H, Si N, Yang J, Bian B, Zhao H (2019) Anti-inflammatory and Regulatory Effects of Huanglian Jiedu Decoction on Lipid Homeostasis and the TLR4/MyD88 Signaling Pathway in LPS-Induced Zebrafish. Front Physiol 10:1241

Zhou J, Tang L, Wang JS (2019) Assessment of the adverse impacts of aflatoxin B1 on gut-microbiota dependent metabolism in F344 rats. Chemosphere 217:618-628

Zoni E, Minoli M, Bovet C, Wehrhan A, Piscuoglio S, Ng CKY, Gray PC, Spahn M, Thalmann GN, Kruithof-de Julio M (2019) Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification. BMC Cancer 19:1216

Zou D, Meng X, Wang B, Dai Y, Yang R, Suo Y, Wu Y, Yang W, Lin R (2019) Analysis of pharmacological mechanisms and targets mining of Wuzi-Yanzong-Wan for treating non-obstructive oligoasthenospermia. Biomed Pharmacother 115:108898

Zou Y, Palte MJ, Deik AA, Li H, Eaton JK, Wang W, Tseng YY, Deasy R, Kost-Alimova M, Dancik V, Leshchiner ES, Viswanathan VS, Signoretti S, Choueiri TK, Boehm JS, Wagner BK, Doench JG, Clish CB, Clemons PA, Schreiber SL (2019) A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nat Commun 10:1617

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2018

Adamczyk B, Jin C, Polom K, Munoz P, Rojas-Macias MA, Zeeberg D, Boren M, Roviello F, Karlsson NG (2018) Sample handling of gastric tissue and O-glycan alterations in paired gastric cancer and non-tumorigenic tissues. Sci Rep 8:242

Alcoriza-Balaguer MI, Garcia-Canaveras JC, Lopez A, Conde I, Juan O, Carretero J, Lahoz A (2018) LipidMS: an R package for lipid annotation in untargeted liquid chromatography-data independent acquisition-mass spectrometry lipidomics. Anal Chem (in press)

Ali N, Schwarzenberg A, Yvin JC, Hosseini SA (2018) Regulatory Role of Silicon in Mediating Differential Stress Tolerance Responses in Two Contrasting Tomato Genotypes Under Osmotic Stress. Front Plant Sci 9:1475

Aquino A, Alexandrino GL, Guest PC, Augusto F, Gomes AF, Murgu M, Steiner J, Martins-de-Souza D (2018) Blood-Based Lipidomics Approach to Evaluate Biomarkers Associated With Response to Olanzapine, Risperidone, and Quetiapine Treatment in Schizophrenia Patients. Front Psychiatry 9:209

Berkecz R, Kormoczi T, Tomosi F, Szegedi V, Horvath J, Kovacs N, Janaky T (2018) Plasma phospholipid profiling of a mouse model of anxiety disorder by hydrophilic interaction liquid chromatography coupled to high-resolution mass spectrometry. Biomed Chromatogr 32:e4202

Berkecz R, Tomosi F, Kormoczi T, Szegedi V, Horvath J, Janaky T (2018) Comprehensive phospholipid and sphingomyelin profiling of different brain regions in mouse model of anxiety disorder using online two-dimensional (HILIC/RP)-LC/MS method. J Pharm Biomed Anal 149:308-317

Beyoglu D, Zhou Y, Chen C, Idle JR (2018) Mass isotopomer-guided decluttering of metabolomic data to visualize endogenous biomarkers of drug toxicity. Biochem Pharmacol 156:491-500

Boccard J, Tonoli D, Strajhar P, Jeanneret F, Odermatt A, Rudaz S (2018) Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening. Talanta 195:77-86

Boxler MI, Streun GL, Liechti ME, Schmid Y, Kraemer T, Steuer AE (2018) Human Metabolome Changes after a Single Dose of 3,4-Methylenedioxymethamphetamine (MDMA) with Special Focus on Steroid Metabolism and Inflammation Processes. J Proteome Res 17:2900-2907

Cao B, Jin M, Brietzke E, McIntyre RS, Wang D, Rosenblat JD, Ragguett RM, Zhang C, Sun X, Rong C, Wang J (2018) Serum metabolic profiling using small molecular water-soluble metabolites in individuals with schizophrenia: A longitudinal study using a pre-post-treatment design. Psychiatry Clin Neurosci (in press)

Chen C, Fan Z, Xu H, Tan X, Zhu M (2018) Metabolomics-based parallel discovery of xenobiotics and induced endogenous metabolic dysregulation in clinical toxicology. Biomed Chromatogr:e4413

Chen S, Zhang M, Bo L, Li S, Hu L, Zhao X, Sun C (2018) Metabolomic analysis of the toxic effect of chronic exposure of cadmium on rat urine. Environ Sci Pollut Res Int 25:3765-3774

Chen T, You Y, Xie G, Zheng X, Zhao A, Liu J, Zhao Q, Wang S, Huang F, Rajani C, Wang C, Chen S, Ni Y, Yu H, Deng Y, Wang X, Jia W (2018) Strategy for an Association Study of the Intestinal Microbiome and Brain Metabolome Across the Lifespan of Rats. Anal Chem 90:2475-2483

Chen XQ, Elsheikha HM, Hu RS, Hu GX, Guo SL, Zhou CX, Zhu XQ (2018) Hepatic Metabolomics Investigation in Acute and Chronic Murine Toxoplasmosis. Front Cell Infect Microbiol 8:189

Cheng M, Wu H, Liu X, Zhou A (2018) Metabolic profiling of copper-laden hepatolenticular degeneration model rats and the interventional effects of Gandou decoction using UPLC-Q-TOF/MS. J Pharm Biomed Anal 164:187-195

Cheng X, Liu X, Guo Z, Sun H, Zhang M, Ji Z, Sun W (2018) Metabolomics of Non-muscle Invasive Bladder Cancer: Biomarkers for Early Detection of Bladder Cancer. Front Oncol 8:494

Delplancke TDJ, de Seymour JV, Tong C, Sulek K, Xia Y, Zhang H, Han TL, Baker PN (2018) Analysis of sequential hair segments reflects changes in the metabolome across the trimesters of pregnancy. Sci Rep 8:36

Dong Y, Qiu P, Zhao L, Zhang P, Huang X, Li C, Chai K, Shou D (2018) Metabolomics study of the hepatoprotective effect of Phellinus igniarius in chronic ethanol-induced liver injury mice using UPLC-Q/TOF-MS combined with ingenuity pathway analysis. Phytomedicine (in press)

Drouin N, Rudaz S, Schappler J (2018) New supported liquid membrane for electromembrane extraction of polar basic endogenous metabolites. J Pharm Biomed Anal 159:53-59

Du H, Wang L, Liu B, Wang J, Su H, Zhang T, Huang Z (2018) Analysis of the Metabolic Characteristics of Serum Samples in Patients With Multiple Myeloma. Front Pharmacol 9:884

Dubbelman AC, Cuyckens F, Dillen L, Gross G, Vreeken RJ, Hankemeier T (2018) Mass spectrometric recommendations for Quan/Qual analysis using liquid-chromatography coupled to quadrupole time-of-flight mass spectrometry. Anal Chim Acta 1020:62-75

Fainberg HP, Birtwistle M, Alagal R, Alhaddad A, Pope M, Davies G, Woods R, Castellanos M, May ST, Ortori CA, Barrett DA, Perry V, Wiens F, Stahl B, van der Beek E, Sacks H, Budge H, Symonds ME (2018) Transcriptional analysis of adipose tissue during development reveals depot-specific responsiveness to maternal dietary supplementation. Sci Rep 8:9628

Feng J, Zhao F, Sun J, Lin B, Zhao L, Liu Y, Jin Y, Li S, Li A, Wei Y (2018) Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients. Int J Cancer (in press)

Fennell TR, Watson SL, Dhungana S, Snyder RW (2018) Metabolism of 4-methylimidazole in Fischer 344 rats and B6C3F1 mice. Food Chem Toxicol 123:181-194

Finelli MJ, Paramo T, Pires E, Ryan BJ, Wade-Martins R, Biggin PC, McCullagh J, Oliver PL (2018) Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase. Mol Neurobiol

Floris P, Curtin S, Kaisermayer C, Lindeberg A, Bones J (2018) Development of a versatile high-temperature short-time (HTST) pasteurization device for small-scale processing of cell culture medium formulations. Appl Microbiol Biotechnol 102:5495-5504

French KE, Harvey J, McCullagh JSO (2018) Targeted and Untargeted Metabolic Profiling of Wild Grassland Plants identifies Antibiotic and Anthelmintic Compounds Targeting Pathogen Physiology, Metabolism and Reproduction. Sci Rep 8:1695

Gao HL, Zhang AH, Yu JB, Sun H, Kong L, Wang XQ, Yan GL, Liu L, Wang XJ (2018) High-throughput lipidomics characterize key lipid molecules as potential therapeutic targets of Kaixinsan protects against Alzheimer's disease in APP/PS1 transgenic mice. J Chromatogr B Analyt Technol Biomed Life Sci 1092:286-295

Gao Y, Chen Y, Yue X, He J, Zhang R, Xu J, Zhou Z, Wang Z, Abliz Z (2018) Development of simultaneous targeted metabolite quantification and untargeted metabolomics strategy using dual-column liquid chromatography coupled with tandem mass spectrometry. Anal Chim Acta 1037:369-379

Ghosson H, Schwarzenberg A, Jamois F, Yvin JC (2018) Simultaneous untargeted and targeted metabolomics profiling of underivatized primary metabolites in sulfur-deficient barley by ultra-high performance liquid chromatography-quadrupole/time-of-flight mass spectrometry. Plant Methods 14:62

Gil A, Zhang W, Wolters JC, Permentier H, Boer T, Horvatovich P, Heiner-Fokkema MR, Reijngoud DJ, Bischoff R (2018) One- vs two-phase extraction: re-evaluation of sample preparation procedures for untargeted lipidomics in plasma samples. Anal Bioanal Chem (in press)

Goncalves E, Lozano-Sanchez J, Gomes S, Ferreira MSL, Cameron LC, Segura-Carretero A (2018) Byproduct Generated During the Elaboration Process of Isotonic Beverage as a Natural Source of Bioactive Compounds. J Food Sci 83:2478-2488

Gonzales GB, De Saeger S (2018) Elastic net regularized regression for time-series analysis of plasma metabolome stability under sub-optimal freezing condition. Sci Rep 8:3659

Guo XD, Liu L, Xiao HY (2018) High-throughput metabolomics for discovering metabolic biomarkers from intestinal tumorigenesis in APC (min/+) mice based on liquid chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 1100-1101:131-139

Guo XH, Cheng XL, Liu WX, Li MH, Wei F, Ma SC (2018) Identification of velvet antler and its mixed varieties by UPLC-QTOF-MS combined with principal component analysis. J Pharm Biomed Anal 165:18-23

Gutierrez DB, Gant-Branum RL, Romer CE, Farrow MA, Allen JL, Dahal N, Nei YW, Codreanu SG, Jordan AT, Palmer LD, Sherrod SD, McLean JA, Skaar EP, Norris JL, Caprioli RM (2018) An Integrated, High-Throughput Strategy for Multiomic Systems Level Analysis. J Proteome Res 17:3396-3408

Hale LJ, Howden SE, Phipson B, Lonsdale A, Er PX, Ghobrial I, Hosawi S, Wilson S, Lawlor KT, Khan S, Oshlack A, Quinlan C, Lennon R, Little MH (2018) 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening. Nat Commun 9:5167

Hale OJ, Ryumin P, Brown JM, Morris M, Cramer R (2018) Production and analysis of multiply charged negative ions by liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom (in press)

Hao L, Wang J, Page D, Asthana S, Zetterberg H, Carlsson C, Okonkwo OC, Li L (2018) Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer's Disease. Sci Rep 8:9291

Hogan SR, Phan JH, Alvarado-Velez M, Wang MD, Bellamkonda RV, Fernandez FM, LaPlaca MC (2018) Discovery of Lipidome Alterations Following Traumatic Brain Injury via High-Resolution Metabolomics. J Proteome Res 17:2131-2143

Hou JJ, Cao CM, Xu YW, Yao S, Cai LY, Long HL, Bi QR, Zhen YY, Wu WY, Guo DA (2018) Exploring lipid markers of the quality of coix seeds with different geographical origins using supercritical fluid chromatography mass spectrometry and chemometrics. Phytomedicine 45:1-7

Housley L, Magana AA, Hsu A, Beaver LM, Wong CP, Stevens JF, Choi J, Jiang Y, Bella D, Williams DE, Maier CS, Shannon J, Dashwood RH, Ho E (2018) Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts. Mol Nutr Food Res (in press)

Huang H, Yao Q, Xia E, Gao L (2018) Metabolomics and Transcriptomics Analyses Reveal Nitrogen Influences on the Accumulation of Flavonoids and Amino Acids in Young Shoots of Tea Plant ( Camellia sinensis L.) Associated with Tea Flavor. J Agric Food Chem 66:9828-9838

Hurlock AK, Wang K, Takeuchi T, Horn PJ, Benning C (2018) In vivo lipid 'tag and track' approach shows acyl editing of plastid lipids and chloroplast import of phosphatidylglycerol precursors in Arabidopsis thaliana. Plant J (in press)

Huynh K, Banach E, Reinhold D (2018) Transformation, Conjugation, and Sequestration Following the Uptake of Triclocarban by Jalapeno Pepper Plants. J Agric Food Chem 66:4032-4043

Izzi-Engbeaya C, Comninos AN, Clarke SA, Jomard A, Yang L, Jones S, Abbara A, et al. (2018) The effects of kisspeptin on beta-cell function, serum metabolites and appetite in humans. Diabetes Obes Metab 20:2800-2810

Ji H, Liu Y, He F, An R, Du Z (2018) LC-MS based urinary metabolomics study of the intervention effect of aloe-emodin on hyperlipidemia rats. J Pharm Biomed Anal 156:104-115

Kang C, Zhao D, Kang L, Wang S, Lv C, Zhou L, Jiang JY, Yang W, Li J, Huang LQ, Guo L (2018) Elucidation of Characteristic Sulfur-Fumigated Markers and Chemical Transformation Mechanism for Quality Control of Achyranthes bidentate Blume Using Metabolome and Sulfur Dioxide Residue Analysis. Front Plant Sci 9:790

Kearney SM, Gibbons SM, Poyet M, Gurry T, Bullock K, Allegretti JR, Clish CB, Alm EJ (2018) Endospores and other lysis-resistant bacteria comprise a widely shared core community within the human microbiota. Isme J (in press)

Kharyuk P, Nazarenko D, Oseledets I, Rodin I, Shpigun O, Tsitsilin A, Lavrentyev M (2018) Employing fingerprinting of medicinal plants by means of LC-MS and machine learning for species identification task. Sci Rep 8:17053

Kim J, Lyu XM, Lee JJL, Zhao G, Chin SF, Yang L, Chen WN (2018) Metabolomics analysis of Pseudomonas chlororaphis JK12 algicidal activity under aerobic and micro-aerobic culture condition. AMB Express 8:131

King AM, Grant I, Rainville PD, Isaac G, Coen M, Wilson ID, Plumb RS (2018) Capillary ultra performance liquid chromatography-tandem mass spectrometry analysis of tienilic acid metabolites in urine following intravenous administration to the rat. J Chromatogr B Analyt Technol Biomed Life Sci 1087-1088:142-148

Knott ME, Manzi M, Zabalegui N, Salazar MO, Puricelli LI, Monge ME (2018) Metabolic Footprinting of a Clear Cell Renal Cell Carcinoma in Vitro Model for Human Kidney Cancer Detection. J Proteome Res 17:3877-3888

Le Pogam P, Doue M, Le Page Y, Habauzit D, Zhadobov M, Sauleau R, Le Drean Y, Rondeau D (2018) Untargeted Metabolomics Reveal Lipid Alterations upon 2-Deoxyglucose Treatment in Human HaCaT Keratinocytes. J Proteome Res 17:1146-1157

Lei G, Zhang HY, Wang ZH, Wei LX, Fu P, Song JB, Fu DH, Huang YJ, Liao JL (2018) High Nighttime Temperature Induces Antioxidant Molecule Perturbations in Heat-Sensitive and Heat-Tolerant Coisogenic Rice ( Oryza sativa) Strains. J Agric Food Chem 66:12131-12140

Li H, Xu W, Jiang L, Gu H, Li M, Zhang J, Guo W, Deng P, Long H, Bu Q, Tian J, Zhao Y, Cen X (2018) Lipidomic signature of serum from the rats exposed to alcohol for one year. Toxicol Lett 294:166-176

Li X, Tian T (2018) Phytochemical Characterization of Mentha spicata L. Under Differential Dried-Conditions and Associated Nephrotoxicity Screening of Main Compound With Organ-on-a-Chip. Front Pharmacol 9:1067

Liang J, He J (2018) Protective role of anthocyanins in plants under low nitrogen stress. Biochem Biophys Res Commun 498:946-953

Liang P, Li R, Sun H, Zhang M, Cheng W, Chen L, Cheng X, Akoh CC (2018) Phospholipids composition and molecular species of large yellow croaker (Pseudosciaena crocea) roe. Food Chem 245:806-811

Lin Z, Ye W, Zu X, Xie H, Li H, Li Y, Zhang W (2018) Integrative metabolic and microbial profiling on patients with Spleen-yang-deficiency syndrome. Sci Rep 8:6619

Liu HF, Luo C, Song W, Shen H, Li G, He ZG, Chen WG, Cao YY, Huang F, Tang SW, Hong P, Zhao EF, Zhu J, He D, Wang S, Huo GY, Liu H (2018) Flavonoid biosynthesis controls fiber color in naturally colored cotton. PeerJ 6:e4537

Liu L, Yin TL, Chen Y, Li Y, Yin L, Ding J, Yang J, Feng HL (2018) Follicular dynamics of glycerophospholipid and sphingolipid metabolisms in polycystic ovary syndrome patients. J Steroid Biochem Mol Biol 185:142-149

Liu X, Cheng X, He L, Zhang W, Wang Y, Sun W, Ji Z (2018) Investigation of the urinary metabolic variations and the application in bladder cancer biomarker discovery. Int J Cancer 143:408-418

Liu Y, Li J, Jin Y, Zhao L, Zhao F, Feng J, Li A, Wei Y (2018) Splenectomy Leads to Amelioration of Altered Gut Microbiota and Metabolome in Liver Cirrhosis Patients. Front Microbiol 9:963

Liu Y, Wang Q, Yang J, Guo X, Liu W, Ma S, Li S (2018) Polygonum multiflorum Thunb.: A Review on Chemical Analysis, Processing Mechanism, Quality Evaluation, and Hepatotoxicity. Front Pharmacol 9:364

Lou Y, Wang Q, Zheng J, Wang X, Jiang W, Zheng Y, Zhao Q, Qiu Y, Zeng S (2018) Identification of the Novel Capecitabine Metabolites in Capecitabine-Treated Patients with Hand-Foot Syndrome. Chem Res Toxicol 31:1069-1079

Lu D, Sun F, Zhou Y (2018) Insights into anaerobic transformation of key dissolved organic matters produced by thermal hydrolysis sludge pretreatment. Bioresour Technol 266:60-67

Lu D, Xiao K, Chen Y, Soh YNA, Zhou Y (2018) Transformation of dissolved organic matters produced from alkaline-ultrasonic sludge pretreatment in anaerobic digestion: From macro to micro. Water Res 142:138-146

Mi N, Cheng T, Li H, Yang P, Mu X, Wang X, Zu X, Qi X, Guo X, Ye J, Zhang W (2018) Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis. J Pharm Biomed Anal 164:70-85

Mi S, Shang K, Jia W, Zhang CH, Li X, Fan YQ, Wang H (2018) Characterization and discrimination of Taihe black-boned silky fowl (Gallus gallus domesticus Brisson) muscles using LC/MS-based lipidomics. Food Res Int 109:187-195

Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB, Chouchani ET (2018) Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature 560:102-106

Misra BB, Mohapatra S (2018) Tools and Resources for Metabolomics Research Community: A 2017-2018 update. Electrophoresis (in press)

Montero-Vargas JM, Casarrubias-Castillo K, Martinez-Gallardo N, Ordaz-Ortiz JJ, Delano-Frier JP, Winkler R (2018) Modulation of steroidal glycoalkaloid biosynthesis in tomato (Solanum lycopersicum) by jasmonic acid. Plant Sci 277:155-165

Mu Y, Lin X, Wang Z, Hou Q, Wang Y, Hu Z (2018) High-production dairy cattle exhibit different rumen and fecal bacterial community and rumen metabolite profile than low-production cattle. Microbiologyopen:e00673

Oliveira JPS, Koblitz MGB, Ferreira MSL, Cameron LC, Macedo AF (2018) Comparative metabolomic responses to gibberellic acid and 6-benzylaminopurine in Cunila menthoides Benth. (Lamiaceae): a contribution to understand the metabolic pathways. Plant Cell Rep 37:1173-1185

Oppong-Danquah E, Parrot D, Blumel M, Labes A, Tasdemir D (2018) Molecular Networking-Based Metabolome and Bioactivity Analyses of Marine-Adapted Fungi Co-cultivated With Phytopathogens. Front Microbiol 9:2072

Park SH, Kyndt J, Chougule K, Park JJ, Brown JK (2018) Low-phosphate-selected Auxenochlorella protothecoides redirects phosphate to essential pathways while producing more biomass. PLoS One 13:e0198953

Pimenta do Nascimento T, Barros Santos MC, Ribeiro da Silva Lima L, Ramos Nascimento F, Cameron LC, Simoes Larraz Ferreira M (2018) Dataset on phenolic profile of seven wheat genotypes along maturation. Data Brief 21:284-288

Pimentel G, Burton KJ, von Ah U, Butikofer U, Pralong FP, Vionnet N, Portmann R, Vergeres G (2018) Metabolic Footprinting of Fermented Milk Consumption in Serum of Healthy Men. J Nutr 148:851-860

Qi P, Zheng Y, Shen Y, Wang J, Bi Q, Feng R, Yang M, Hou J, Wu W, Sun S (2018) Characterization and discrimination of steroidal saponins in Tribulus terrestris L. and its three different aerial parts by chemical profiling with chemometrics analysis. J Sep Sci 41:4212-4221

Qiao Y, Liu G, Leng C, Zhang Y, Lv X, Chen H, Sun J, Feng Z (2018) Metabolic profiles of cysteine, methionine, glutamate, glutamine, arginine, aspartate, asparagine, alanine and glutathione in Streptococcus thermophilus during pH-controlled batch fermentations. Sci Rep 8:12441

Ran H, Zhu Y, Deng R, Zhang Q, Liu X, Feng M, Zhong J, Lin S, Tong X, Su Q (2018) Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN. J Exp Clin Cancer Res 37:54

Rey G, Milev NB, Valekunja UK, Ch R, Ray S, Silva Dos Santos M, Nagy AD, Antrobus R, MacRae JI, Reddy AB (2018) Metabolic oscillations on the circadian time scale in Drosophila cells lacking clock genes. Mol Syst Biol 14:e8376

Rindlisbacher B, Schmid C, Geiser T, Bovet C, Funke-Chambour M (2018) Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis - a potential biomarker role for LysoPC. Respir Res 19:7

Rusilowicz MJ, Dickinson M, Charlton AJ, O'Keefe S, Wilson J (2018) MetaboClust: Using interactive time-series cluster analysis to relate metabolomic data with perturbed pathways. PLoS One 13:e0205968

Sato K, Saigusa D, Saito R, Fujioka A, Nakagawa Y, Nishiguchi KM, Kokubun T, Motoike IN, Maruyama K, Omodaka K, Shiga Y, Uruno A, Koshiba S, Yamamoto M, Nakazawa T (2018) Metabolomic changes in the mouse retina after optic nerve injury. Sci Rep 8:11930

Schada von Borzyskowski L, Carrillo M, Leupold S, Glatter T, Kiefer P, Weishaupt R, Heinemann M, Erb TJ (2018) An engineered Calvin-Benson-Bassham cycle for carbon dioxide fixation in Methylobacterium extorquens AM1. Metab Eng 47:423-433

Schweizer F, Colinas M, Pollier J, Van Moerkercke A, Vanden Bossche R, de Clercq R, Goossens A (2018) An engineered combinatorial module of transcription factors boosts production of monoterpenoid indole alkaloids in Catharanthus roseus. Metab Eng 48:150-162

Shen J, Zou Z, Zhang X, Zhou L, Wang Y, Fang W, Zhu X (2018) Metabolic analyses reveal different mechanisms of leaf color change in two purple-leaf tea plant (Camellia sinensis L.) cultivars. Hortic Res 5:7

Shetage SS, Traynor MJ, Brown MB, Chilcott RP (2018) Sebomic identification of sex- and ethnicity-specific variations in residual skin surface components (RSSC) for bio-monitoring or forensic applications. Lipids Health Dis 17:194

Shi T, Burton S, Wang Y, Xu S, Zhang W, Yu L (2018) Metabolomic analysis of honey bee, Apis mellifera L. response to thiacloprid. Pestic Biochem Physiol 152:17-23

Shi X, Yang W, Qiu S, Hou J, Wu W, Guo D (2018) Systematic profiling and comparison of the lipidomes from Panax ginseng, P. quinquefolius, and P. notoginseng by ultrahigh performance supercritical fluid chromatography/high-resolution mass spectrometry and ion mobility-derived collision cross section measurement. J Chromatogr A 1548:64-75

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Shin JH, Nam MH, Lee H, Lee JS, Kim H, Chung MJ, Seo JG (2018) Amelioration of obesity-related characteristics by a probiotic formulation in a high-fat diet-induced obese rat model. Eur J Nutr 57:2081-2090

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Williamson BK, Hawkey NM, Blake DA, Frenkel JW, McDaniel KP, Davis JK, Satija C, Beazer A, Dhungana S, Carlson J, McRitchie S, Ayyala RS (2018) The Effects of Glaucoma Drainage Devices on Oxygen Tension, Glycolytic Metabolites, and Metabolomics Profile of Aqueous Humor in the Rabbit. Transl Vis Sci Technol 7:14

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Wu J, Yang W, Pan H, Yao S, Wu W, Guo D (2018) Geographic impact evaluation of the quality of Alismatis Rhizoma by untargeted metabolomics and quantitative assay. J Sep Sci 41:839-846

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Wu SY, Phan NN, Ho SH, Lai YH, Tsai CH, Yang CH, Yu HG, Wang JC, Huang PL, Lin YC (2018) Metabolomic assessment of arsenite toxicity and novel biomarker discovery in early development of zebrafish embryos. Toxicol Lett 290:116-122

Xia F, Li A, Chai Y, Xiao X, Wan J, Li P, Wang Y (2018) UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar. Front Pharmacol 9:618

Xiao HH, Sham TT, Chan CO, Li MH, Chen X, Wu QC, Mok DK, Yao XS, Wong MS (2018) A Metabolomics Study on the Bone Protective Effects of a Lignan-Rich Fraction From Sambucus Williamsii Ramulus in Aged Rats. Front Pharmacol 9:932

Xie C, Gao X, Sun D, Zhang Y, Krausz KW, Qin X, Gonzalez FJ (2018) Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2alpha Inhibitor PT2385 In Vivo and In Vitro. Drug Metab Dispos 46:336-345

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Xu Y, Chen S, Yu T, Qiao J, Sun G (2018) High-throughput metabolomics investigates anti-osteoporosis activity of oleanolic acid via regulating metabolic networks using ultra-performance liquid chromatography coupled with mass spectrometry. Phytomedicine 51:68-76

Yan K, Chen W, Zhu H, Lin G, Sun W, Liu X, Pan H, Wang L, Yang H, Liu M, Gong F (2018) The Changes of Serum Metabolites in Diabetic GK Rats after Ileal Transposition Surgery. Obes Surg (in press)

Yang X, Wei S, Liu B, Guo D, Zheng B, Feng L, Liu Y, Tomas-Barberan FA, Luo L, Huang D (2018) A novel integrated non-targeted metabolomic analysis reveals significant metabolite variations between different lettuce (Lactuca sativa. L) varieties. Hortic Res 5:33

Yang ZR, Wang ZH, Tang JF, Yan Y, Yue SJ, Feng WW, Shi ZY, Meng XT, Peng C, Wang CY, Meng DL, Yan D (2018) UPLC-QTOF/MS(E) and Bioassay Are Available Approaches for Identifying Quality Fluctuation of Xueshuantong Lyophilized Powder in Clinic. Front Pharmacol 9:633

Yu J, Mo L, Pan L, Yao C, Ren D, An X, Tsogtgerel T, Zhang H, Liu W (2018) Bacterial Microbiota and Metabolic Character of Traditional Sour Cream and Butter in Buryatia, Russia. Front Microbiol 9:2496

Yu Q, He Z, Zubkov D, Huang S, Kurochkin I, Yang X, Halene T, Willmitzer L, Giavalisco P, Akbarian S, Khaitovich P (2018) Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders. Mol Psychiatry (in press)

Yu Z, Miller HC, Puzon GJ, Clowers BH (2018) Application of untargeted metabolomics for the detection of pathogenic Naegleria fowleri in an operational drinking water distribution system. Water Res 145:678-686

Yue W, Sun W, Rao RSP, Ye N, Yang Z, Chen M (2018) Non-targeted metabolomics reveals distinct chemical compositions among different grades of Bai Mudan white tea. Food Chem 277:289-297

Zhan ZL, Deng AP, Kang LP, Tang JF, Nan TG, Chen T, He YL, Guo LP, Huang LQ (2018) Chemical profiling in Moutan Cortex after sulfuring and desulfuring processes reveals further insights into the quality control of TCMs by nontargeted metabolomic analysis. J Pharm Biomed Anal 156:340-348

Zhang M, Jia S, Liu Y, Li S, Bo L, Zhao X, Sun C (2018) Metabonomics analysis of kidneys in rats administered with chronic low-dose cadmium by ultra-performance liquid chromatography-mass spectrometry. J Appl Toxicol (in press)

Zhang YD, Li P, Zheng N, Jia ZW, Meruva N, Ladak A, Cleland G, Wen F, Li SL, Zhao SG, Wang JQ (2018) A metabolomics approach to characterize raw, pasteurized, and ultra-high temperature milk using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry and multivariate data analysis. J Dairy Sci 101:9630-9636

Zhang ZH, Li MH, Liu D, Chen H, Chen DQ, Tan NH, Ma SC, Zhao YY (2018) Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-beta/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney Disease. Front Pharmacol 9:1029

Zhao H, Chong J, Tang R, Li L, Xia J, Li D (2018) Metabolomics investigation of dietary effects on flesh quality in grass carp (Ctenopharyngodon idellus). Gigascience 7 (in press)

Zhao Q, Zhao N, Ye X, He M, Yang Y, Gao H, Zhang X (2018) Rapid discrimination between red and white ginseng based on unique mass-spectrometric features. J Pharm Biomed Anal 164:202-210

Zhao S, Liu Z, Wang M, He D, Liu L, Shu Y, Song Z, Li H, Liu Y, Lu A (2018) Anti-inflammatory effects of Zhishi and Zhiqiao revealed by network pharmacology integrated with molecular mechanism and metabolomics studies. Phytomedicine 50:61-72

Zheng W, Wu X, Goudarzi M, Shi J, Song W, Li C, Liu J, Chen H, Zhang X, Zeng X, Li HH (2018) Metabolomic alterations associated with Behcet's disease. Arthritis Res Ther 20:214

Zhou CX, Cong W, Chen XQ, He SY, Elsheikha HM, Zhu XQ (2018) Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry. Front Microbiol 8:2612

Zhou J, Tang L, Wang JS (2018) Assessment of the adverse impacts of aflatoxin B1 on gut-microbiota dependent metabolism in F344 rats. Chemosphere 217:618-628

Zhou M, Gan Y, He C, Chen Z, Jia Y (2018) Lipidomics reveals skin surface lipid abnormity in acne in young men. Br J Dermatol (in press)

Zhou Z, Tu J, Zhu ZJ (2018) Advancing the large-scale CCS database for metabolomics and lipidomics at the machine-learning era. Curr Opin Chem Biol 42:34-41

Zufferey F, Rahban R, Garcia A, Gagnebin Y, Boccard J, Tonoli D, Jeanneret F, Stettler E, Senn A, Nef S, Rudaz S, Rossier MF (2018) Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men. Clin Biochem (in press)

Zuther E, Schaarschmidt S, Fischer A, Erban A, Pagter M, Mubeen U, Giavalisco P, Kopka J, Sprenger H, Hincha DK (2018) Molecular signatures of increased freezing tolerance due to low temperature memory in Arabidopsis. Plant Cell Environ (in press)

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2017

Abdelrazig S, Ortori CA, Davey G, Deressa W, Mulleta D, Barrett DA, Amberbir A, Fogarty AW (2017) A metabolomic analytical approach permits identification of urinary biomarkers for Plasmodium falciparum infection: a case-control study. Malar J 16:229

Al Hamimi S, Heyman-Linden L, Plaza M, Turner C, Berger K, Spegel P (2017) Alterations in the plasma metabolite profile associated with improved hepatic function and glycemia in mice fed lingonberry supplemented high-fat diets. Mol Nutr Food Res 61

Artegoitia VM, Foote AP, Lewis RM, Freetly HC (2017) Rumen Fluid Metabolomics Analysis Associated with Feed Efficiency on Crossbred Steers. Sci Rep 7:2864

Bao W, Cao C, Li S, Bo L, Zhang M, Zhao X, Liu Y, Sun C (2017) Metabonomic analysis of quercetin against the toxicity of acrylamide in rat urine. Food Funct 8:1204-1214

Bozek K, Khrameeva EE, Reznick J, Omerbasic D, Bennett NC, Lewin GR, Azpurua J, Gorbunova V, Seluanov A, Regnard P, Wanert F, Marchal J, Pifferi F, Aujard F, Liu Z, Shi P, Paabo S, Schroeder F, Willmitzer L, Giavalisco P, Khaitovich P (2017) Lipidome determinants of maximal lifespan in mammals. Sci Rep 7:5

Carey AN, Zhang W, Setchell KDR, Simmons JR, Shi T, Lages CS, Mullen M, Carroll K, Karns R, Bessho K, Sheridan R, Zhao X, Weber SN, Miethke AG (2017) Hepatic MDR3 expression impacts lipid homeostasis and susceptibility to inflammatory bile duct obstruction in neonates. Pediatr Res 82:122-132

Charkoftaki G, Chen Y, Han M, Sandoval M, Yu X, Zhao H, Orlicky DJ, Thompson DC, Vasiliou V (2017) Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function. Chem Biol Interact 276:15-22

Chen DQ, Cao G, Chen H, Liu D, Su W, Yu XY, Vaziri ND, Liu XH, Bai X, Zhang L, Zhao YY (2017) Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/beta-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease. Redox Biol 12:505-521

Chen H, Chen L, Liu D, Chen DQ, Vaziri ND, Yu XY, Zhang L, Su W, Bai X, Zhao YY (2017) Combined Clinical Phenotype and Lipidomic Analysis Reveals the Impact of Chronic Kidney Disease on Lipid Metabolism. J Proteome Res 16:1566-1578

Chen XQ, Zhou CX, Elsheikha HM, He S, Hu GX, Zhu XQ (2017) Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis. Parasit Vectors 10:339

Choi HS, Kim S, Kim MJ, Kim MS, Kim J, Park CW, Seo D, Shin SS, Oh SW (2017) Efficacy and safety of Panax ginseng berry extract on glycemic control: A 12-wk randomized, double-blind, and placebo-controlled clinical trial. J Ginseng Res 42:90-97

Choo JM, Trim PJ, Leong LEX, Abell GCJ, Brune C, Jeffries N, Wesselingh S, Dear TN, Snel MF, Rogers GB (2017) Inbred Mouse Populations Exhibit Intergenerational Changes in Intestinal Microbiota Composition and Function Following Introduction to a Facility. Front Microbiol 8:608

Dorival-Garcia N, Bones J (2017) Monitoring leachables from single-use bioreactor bags for mammalian cell culture by dispersive liquid-liquid microextraction followed by ultra high performance liquid chromatography quadrupole time of flight mass spectrometry. J Chromatogr A 1512:51-60

Dorival-Garcia N, Larsson I, Bones J (2017) Non-volatile extractable analysis of prefilled syringes for parenteral administration of drug products. J Pharm Biomed Anal 142:337-342

Einarsdottir E, Magnusdottir M, Astarita G, Kock M, Ogmundsdottir HM, Thorsteinsdottir M, Rapp HT, Omarsdottir S, Paglia G (2017) Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland. Mar Drugs 15

Eloy NB, Voorend W, Lan W, Saleme ML, Cesarino I, Vanholme R, Smith RA, Goeminne G, Pallidis A, Morreel K, Nicomedes J, Jr., Ralph J, Boerjan W (2017) Silencing CHALCONE SYNTHASE in Maize Impedes the Incorporation of Tricin into Lignin and Increases Lignin Content. Plant Physiol 173:998-1016

Floris P, McGillicuddy N, Albrecht S, Morrissey B, Kaisermayer C, Lindeberg A, Bones J (2017) Untargeted LC-MS/MS Profiling of Cell Culture Media Formulations for Evaluation of High Temperature Short Time Treatment Effects. Anal Chem 89:9953-9960

Fluck M, Ruoss S, Mohl CB, Valdivieso P, Benn MC, von Rechenberg B, Laczko E, Hu J, Wieser K, Meyer DC, Gerber C (2017) Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep. J Steroid Biochem Mol Biol 165:382-395

Gagnebin Y, Tonoli D, Lescuyer P, Ponte B, de Seigneux S, Martin PY, Schappler J, Boccard J, Rudaz S (2017) Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies. Anal Chim Acta 955:27-35

Gao K, Zhao H, Gao J, Wen B, Jia C, Wang Z, Zhang F, Wang J, Xie H, Wang W, Chen J (2017) Mechanism of Chinese Medicine Herbs Effects on Chronic Heart Failure Based on Metabolic Profiling. Front Pharmacol 8:864

Garcia-Fernandez E, Koch G, Wagner RM, Fekete A, Stengel ST, Schneider J, Mielich-Suss B, Geibel S, Markert SM, Stigloher C, Lopez D (2017) Membrane Microdomain Disassembly Inhibits MRSA Antibiotic Resistance. Cell 171:1354-1367 e1320

Gethings LA, Richardson K, Wildgoose J, Lennon S, Jarvis S, Bevan CL, Vissers JPC, Langridge JI (2017) Lipid profiling of complex biological mixtures by liquid chromatography/mass spectrometry using a novel scanning quadrupole data-independent acquisition strategy. Rapid Commun Mass Spectrom 31:1599-1606

Gonzalez-Ruiz V, Pezzatti J, Roux A, Stoppini L, Boccard J, Rudaz S (2017) Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry. J Chromatogr A 1527:53-60

Guzman MK, Parween S, Butardo VM, Alhambra CM, Anacleto R, Seiler C, Bird AR, Chow CP, Sreenivasulu N (2017) Investigating glycemic potential of rice by unraveling compositional variations in mature grain and starch mobilization patterns during seed germination. Sci Rep 7:5854

Heyer R, Schallert K, Zoun R, Becher B, Saake G, Benndorf D (2017) Challenges and perspectives of metaproteomic data analysis. J Biotechnol 261:24-36

Hines KM, Waalkes A, Penewit K, Holmes EA, Salipante SJ, Werth BJ, Xu L (2017) Characterization of the Mechanisms of Daptomycin Resistance among Gram-Positive Bacterial Pathogens by Multidimensional Lipidomics. mSphere 2 (In press)

Holt GS, Lodge JK, McCarthy AJ, Graham AK, Young G, Bridge SH, Brown AK, Veses-Garcia M, Lanyon CV, Sails A, Allison HE, Smith DL (2017) Shigatoxin encoding Bacteriophage varphi24B modulates bacterial metabolism to raise antimicrobial tolerance. Sci Rep 7:40424

Huang W, Robert CA, Herve MR, Hu L, Bont Z, Erb M (2017) A mechanism for sequence specificity in plant-mediated interactions between herbivores. New Phytol 214:169-179

Imasawa T, Obre E, Bellance N, Lavie J, Rigothier C, Delmas Y, Combe C, Lacombe D, Benard G, Claverol S, Bonneu M, Rossignol R (2017) High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy. Faseb J 31:294-307

Jiang L, Gu H, Lin Y, Xu W, Zhu R, Kong J, Luo L, Long H, Liu B, Chen B, Zhao Y, Cen X (2017) Remodeling of brain lipidome in methamphetamine-sensitized mice. Toxicol Lett 279:67-76

Jing J, Shi Y, Zhang Q, Wang J, Ruan J (2017) Prediction of Chinese green tea ranking by metabolite profiling using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS). Food Chem 221:311-316

Jones JW, Carter CL, Li F, Yu J, Pierzchalski K, Jackson IL, Vujaskovic Z, Kane MA (2017) Ultraperformance convergence chromatography-high resolution tandem mass spectrometry for lipid biomarker profiling and identification. Biomed Chromatogr 31 (In press)

Kang LP, Huang YY, Zhan ZL, Liu DH, Peng HS, Nan TG, Zhang Y, Hao QX, Tang JF, Zhu SD, Yang G, Guo LP, Chen M, Huang LQ (2017) Structural characterization and discrimination of the Paris polyphylla var. yunnanensis and Paris vietnamensis based on metabolite profiling analysis. J Pharm Biomed Anal 142:252-261

Kim MS, Nam M, Hwang GS (2017) Metabolic Alterations in Two Cirsium Species Identified at Distinct Phenological Stages using UPLC-QTOF/MS. Phytochem Anal 29:77-86

Kind T, Tsugawa H, Cajka T, Ma Y, Lai Z, Mehta SS, Wohlgemuth G, Barupal DK, Showalter MR, Arita M, Fiehn O (2017) Identification of small molecules using accurate mass MS/MS search. Mass Spectrom Rev (In press)

Ku CW, Tan ZW, Lim MK, Tam ZY, Lin CH, Ng SP, Allen JC, Lek SM, Tan TC, Tan NS (2017) Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile. BBA Clin 8:48-55

Kulkarni A, Mateus M, Thinnes CC, McCullagh JS, Schofield CJ, Taylor GP, Bangham CRM (2017) Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1. Cell Chem Biol 24:1377-1387 e1373

Laiakis EC, Pannkuk EL, Chauthe SK, Wang YW, Lian M, Mak TD, Barker CA, Astarita G, Fornace AJ, Jr. (2017) A Serum Small Molecule Biosignature of Radiation Exposure from Total Body Irradiated Patients. J Proteome Res 16:3805-3815

Law KP, Han TL, Mao X, Zhang H (2017) Tryptophan and purine metabolites are consistently upregulated in the urinary metabolome of patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 2. Clin Chim Acta 468:126-139

Law KP, Mao X, Han TL, Zhang H (2017) Unsaturated plasma phospholipids are consistently lower in the patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 1. Clin Chim Acta 465:53-71

Law KP, Zhang H (2017) The pathogenesis and pathophysiology of gestational diabetes mellitus: Deductions from a three-part longitudinal metabolomics study in China. Clin Chim Acta 468:60-70

Li XN, Zhang A, Wang M, Sun H, Liu Z, Qiu S, Zhang T, Wang X (2017) Screening the active compounds of Phellodendri Amurensis cortex for treating prostate cancer by high-throughput chinmedomics. Sci Rep 7:46234

Lin L, Li H, Lin H, Zhang M, Qu C, Yan L, Yin X, Ni J (2017) A New Perspective on Liver Injury by Traditional Chinese Herbs Such As Polygonum multiflorum: The Geographical Area of Harvest As an Important Contributory Factor. Front Pharmacol 8:349

Lin Y, Gu H, Jiang L, Xu W, Liu C, Li Y, Qian X, Li D, Li Z, Hu J, Zhang H, Guo W, Zhao Y, Cen X (2017) Cocaine modifies brain lipidome in mice. Mol Cell Neurosci 85:29-44

Lindner S, Gruhle K, Schmidt R, Garamus VM, Ramsbeck D, Hause G, Meister A, Sinz A, Drescher S (2017) Azide-Modified Membrane Lipids: Synthesis, Properties, and Reactivity. Langmuir 33:4960-4973

Lu S, Han Y, Chu H, Kong L, Zhang A, Yan G, Sun H, Wang P, Wang X (2017) Characterizing serum metabolic alterations of Alzheimer's disease and intervention of Shengmai-San by ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry. Food Funct 8:1660-1671

Mansfeld BN, Colle M, Kang Y, Jones AD, Grumet R (2017) Transcriptomic and metabolomic analyses of cucumber fruit peels reveal a developmental increase in terpenoid glycosides associated with age-related resistance to Phytophthora capsici. Hortic Res 4:17022

Mnich E, Vanholme R, Oyarce P, Liu S, Lu F, Goeminne G, Jorgensen B, Motawie MS, Boerjan W, Ralph J, Ulvskov P, Moller BL, Bjarnholt N, Harholt J (2017) Degradation of lignin beta-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6. Plant Biotechnol J 15:581-593

Moghe GD, Leong BJ, Hurney SM, Daniel Jones A, Last RL (2017) Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway. Elife 6 (In press)

Myint L, Kleensang A, Zhao L, Hartung T, Hansen KD (2017) Joint Bounding of Peaks Across Samples Improves Differential Analysis in Mass Spectrometry-Based Metabolomics. Anal Chem 89:3517-3523

Napavichayanun S, Lutz O, Fischnaller M, Jakschitz T, Bonn G, Aramwit P (2017) Identification and quantification and antioxidant activity of flavonoids in different strains of silk cocoon, Bombyx mori. Arch Biochem Biophys 631:58-65

Ni Z, Angelidou G, Lange M, Hoffmann R, Fedorova M (2017) LipidHunter Identifies Phospholipids by High-Throughput Processing of LC-MS and Shotgun Lipidomics Datasets. Anal Chem 89:8800-8807

Noratto GD, Chew BP, Atienza LM (2017) Red raspberry (Rubus idaeus L.) intake decreases oxidative stress in obese diabetic (db/db) mice. Food Chem 227:305-314

O'Connor A, Brasher CJ, Slatter DA, Meckelmann SW, Hawksworth JI, Allen SM, O'Donnell VB (2017) LipidFinder: A computational workflow for discovery of lipids identifies eicosanoid-phosphoinositides in platelets. JCI Insight 2:e91634

Pabst T, Kortz L, Fiedler GM, Ceglarek U, Idle JR, Beyoglu D (2017) The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease features. BBA Clin 7:105-114

Paglia G, Astarita G (2017) Metabolomics and lipidomics using traveling-wave ion mobility mass spectrometry. Nat Protoc 12:797-813

Pan H, Yang W, Yao C, Shen Y, Zhang Y, Shi X, Yao S, Wu W, Guo D (2017) Mass defect filtering-oriented classification and precursor ions list-triggered high-resolution mass spectrometry analysis for the discovery of indole alkaloids from Uncaria sinensis. J Chromatogr A 1516:102-113

Pannkuk EL, Laiakis EC, Singh VK, Fornace AJ (2017) Lipidomic Signatures of Nonhuman Primates with Radiation-Induced Hematopoietic Syndrome. Sci Rep 7:9777

Patel D, Thompson MD, Manna SK, Krausz KW, Zhang L, Nilubol N, Gonzalez FJ, Kebebew E (2017) Unique and Novel Urinary Metabolomic Features in Malignant versus Benign Adrenal Neoplasms. Clin Cancer Res 23:5302-5310

Pickens CA, Vazquez AI, Jones AD, Fenton JI (2017) Obesity, adipokines, and C-peptide are associated with distinct plasma phospholipid profiles in adult males, an untargeted lipidomic approach. Sci Rep 7:6335

Piltti J, Bygdell J, Qu C, Lammi MJ (2017) Effects of long-term low oxygen tension in human chondrosarcoma cells. J Cell Biochem 119:2320-2332

Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I (2017) Integrated mass spectrometry imaging and omics workflows on the same tissue section using grid-aided, parafilm-assisted microdissection. Biochim Biophys Acta 1861:1702-1714

Randazzo GM, Tonoli D, Strajhar P, Xenarios I, Odermatt A, Boccard J, Rudaz S (2017) Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study. J Chromatogr B Analyt Technol Biomed Life Sci 1071:11-18

Ribeiro MAS, Murgu M, Silva VM, Sawaya A, Ribeiro LF, Justi A, Meurer EC (2017) The screening of organic matter in mineral and tap water by UHPLC-HRMS. Talanta 174:581-586

Rochat B (2017) Proposed Confidence Scale and ID Score in the Identification of Known-Unknown Compounds Using High Resolution MS Data. J Am Soc Mass Spectrom 28:709-723

Rosenmai AK, Bengtstrom L, Taxvig C, Trier X, Petersen JH, Svingen T, Binderup ML, Barbara Medea Alice VV, Dybdahl M, Granby K, Vinggaard AM (2017) An effect-directed strategy for characterizing emerging chemicals in food contact materials made from paper and board. Food Chem Toxicol 106:250-259

Ros-Mazurczyk M, Jelonek K, Marczyk M, Binczyk F, Pietrowska M, Polanska J, Dziadziuszko R, Jassem J, Rzyman W, Widlak P (2017) Serum lipid profile discriminates patients with early lung cancer from healthy controls. Lung Cancer 112:69-74

Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, Deik AA, Pierce KA, Scott JM, Clish CB, Smith DE, Weinberger A, Avnit-Sagi T, Lotan-Pompan M, Segal E, Taylor A (2017) Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration. Proc Natl Acad Sci U S A 114:E4472-E4481

Salazar C, Jones MD, Sturtevant D, Horn PJ, Crossley J, Zaman K, Chapman KD, Wrona M, Isaac G, Smith NW, Shulaev V (2017) Development and application of sub-2-mum particle CO2 -based chromatography coupled to mass spectrometry for comprehensive analysis of lipids in cottonseed extracts. Rapid Commun Mass Spectrom 31:591-605

Sethi S, Brietzke E (2017) Recent advances in lipidomics: Analytical and clinical perspectives. Prostaglandins Other Lipid Mediat 128-129:8-16

Shang J, Castro-Perez JM, Shen X, Zhu Y, Liu H, Qian Y, Previs S, Howard AD, Erion M, Kelley DE, Wang L (2017) Duodenal-jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice. Obesity (Silver Spring) 24:1938-1945

Shen H, Campanello GC, Flicker D, Grabarek Z, Hu J, Luo C, Banerjee R, Mootha VK (2017) The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12. Cell 171:771-782 e711

Shetage SS, Traynor MJ, Brown MB, Galliford TM, Chilcott RP (2017) Application of sebomics for the analysis of residual skin surface components to detect potential biomarkers of type-1 diabetes mellitus. Sci Rep 7:8999

Shin JH, Nam MH, Lee H, Lee JS, Kim H, Chung MJ, Seo JG (2017) Amelioration of obesity-related characteristics by a probiotic formulation in a high-fat diet-induced obese rat model. Eur J Nutr (In press)

Som NF, Heine D, Holmes NA, Munnoch JT, Chandra G, Seipke RF, Hoskisson PA, Wilkinson B, Hutchings MI (2017) The Conserved Actinobacterial Two-Component System MtrAB Coordinates Chloramphenicol Production with Sporulation in Streptomyces venezuelae NRRL B-65442. Front Microbiol 8:1145

Steenackers W, Klima P, Quareshy M, Cesarino I, Kumpf RP, Corneillie S, Araujo P, Viaene T, Goeminne G, Nowack MK, Ljung K, Friml J, Blakeslee JJ, Novak O, Zazimalova E, Napier R, Boerjan W, Vanholme B (2017) cis-Cinnamic Acid Is a Novel, Natural Auxin Efflux Inhibitor That Promotes Lateral Root Formation. Plant Physiol 173:552-565

Tam ZY, Ng SP, Tan LQ, Lin CH, Rothenbacher D, Klenk J, Boehm BO (2017) Metabolite profiling in identifying metabolic biomarkers in older people with late-onset type 2 diabetes mellitus. Sci Rep 7:4392

Tambellini NP, Zaremberg V, Krishnaiah S, Turner RJ, Weljie AM (2017) Primary Metabolism and Medium-Chain Fatty Acid Alterations Precede Long-Chain Fatty Acid Changes Impacting Neutral Lipid Metabolism in Response to an Anticancer Lysophosphatidylcholine Analogue in Yeast. J Proteome Res 16:3741-3752

Tang JF, Li WX, Zhang F, Li YH, Cao YJ, Zhao Y, Li XL, Ma ZJ (2017) Discrimination of Radix Polygoni Multiflori from different geographical areas by UPLC-QTOF/MS combined with chemometrics. Chin Med 12:34

Tebani A, Schmitz-Afonso I, Abily-Donval L, Heron B, Piraud M, Ausseil J, Brassier A, De Lonlay P, Zerimech F, Vaz FM, Gonzalez BJ, Marret S, Afonso C, Bekri S (2017) Urinary metabolic phenotyping of mucopolysaccharidosis type I combining untargeted and targeted strategies with data modeling. Clin Chim Acta 475:7-14

Tipthara P, Kunacheva C, Soh YN, Wong SC, Pin NS, Stuckey DC, Boehm BO (2017) Global Profiling of Metabolite and Lipid Soluble Microbial Products in Anaerobic Wastewater Reactor Supernatant Using UPLC-MSE. J Proteome Res 16:559-570

Verplanken K, Stead S, Jandova R, Poucke CV, Claereboudt J, Bussche JV, Saeger S, Takats Z, Wauters J, Vanhaecke L (2017) Rapid evaporative ionization mass spectrometry for high-throughput screening in food analysis: The case of boar taint. Talanta 169:30-36

Wang J, Qi P, Hou J, Shen Y, Yang M, Bi Q, Deng Y, Shi X, Feng R, Feng Z, Wu W, Guo D (2017) The profiling of the metabolites of hirsutine in rat by ultra-high performance liquid chromatography coupled with linear ion trap Orbitrap mass spectrometry: An improved strategy for the systematic screening and identification of metabolites in multi-samples in vivo. J Pharm Biomed Anal 134:149-157

Wang Y, Feng R, Wang R, Yang F, Li P, Wan JB (2017) Enhanced MS/MS coverage for metabolite identification in LC-MS-based untargeted metabolomics by target-directed data dependent acquisition with time-staggered precursor ion list. Anal Chim Acta 992:67-75 Wen B, Mei Z, Zeng C, Liu S (2017) metaX: a flexible and comprehensive software for processing metabolomics data. BMC Bioinformatics 18:183

Wielogorska E, Chevallier O, Black C, Galvin-King P, Deletre M, Kelleher CT, Haughey SA, Elliott CT (2017) Development of a comprehensive analytical platform for the detection and quantitation of food fraud using a biomarker approach. The oregano adulteration case study. Food Chem 239:32-39

Wu JL, Zhou CX, Wu PJ, Xu J, Guo YQ, Xue F, Getachew A, Xu SF (2017) Brain metabolomic profiling of eastern honey bee (Apis cerana) infested with the mite Varroa destructor. PLoS One 12:e0175573

Xi X, Kwok LY, Wang Y, Ma C, Mi Z, Zhang H (2017) Ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry MSE-based untargeted milk metabolomics in dairy cows with subclinical or clinical mastitis. J Dairy Sci 100:4884-4896

Yang BY, Tan JY, Liu Y, Liu B, Jin S, Guo HW, Kuang HX (2017) A UPLC-TOF/MS-based metabolomics study of rattan stems of Schisandra. chinensis effects on Alzheimer's disease rats model. Biomed Chromatogr (In press)

Yao C, Yang W, Zhang J, Qiu S, Chen M, Shi X, Pan H, Wu W, Guo D (2017) UHPLC-Q-TOF-MS-based metabolomics approach to compare the saponin compositions of Xueshuantong injection and Xuesaitong injection. J Sep Sci 40:834-841

Yoshitomi T, Oshima N, Goto Y, Nakamori S, Wakana D, Anjiki N, Sugimura K, Kawano N, Fuchino H, Iida O, Kagawa T, Jinno H, Kawahara N, Kobayashi Y, Maruyama T (2017) Construction of Prediction Models for the Transient Receptor Potential Vanilloid Subtype 1 (TRPV1)-Stimulating Activity of Ginger and Processed Ginger Based on LC-HRMS Data and PLS Regression Analyses. J Agric Food Chem 65:3581-3588

Yu J, Kong L, Zhang A, Han Y, Liu Z, Sun H, Liu L, Wang X (2017) High-Throughput Metabolomics for Discovering Potential Metabolite Biomarkers and Metabolic Mechanism from the APPswe/PS1dE9 Transgenic Model of Alzheimer's Disease. J Proteome Res 16:3219-3228

Yu Z, Miller HC, Puzon GJ, Clowers BH (2017) Development of Untargeted Metabolomics Methods for the Rapid Detection of Pathogenic Naegleria fowleri. Environ Sci Technol 51:4210-4219

Zang X, Perez JJ, Jones CM, Monge ME, McCarty NA, Stecenko AA, Fernandez FM (2017) Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics. J Am Soc Mass Spectrom 28:1489-1496

Zhang A, Liu Q, Zhao H, Zhou X, Sun H, Nan Y, Zou S, Ma CW, Wang X (2017) Phenotypic characterization of nanshi oral liquid alters metabolic signatures during disease prevention. Sci Rep 6:19333

Zhang R, Zhou Q, Cai X, Dong S, Le Z, Xiao R, Yu H (2017) Lipidomic analysis reveals the significant increase in diacylglycerophosphocholines in umbilical cord blood from pregnant women with gestational hypercholesterolemia. Placenta 59:39-45

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2016

Ali MR, Wu Y, Han T, Zang X, Xiao H, Tang Y, Wu R, Fernandez FM, El-Sayed MA (2016) Simultaneous Time-Dependent Surface-Enhanced Raman Spectroscopy, Metabolomics, and Proteomics Reveal Cancer Cell Death Mechanisms Associated with Gold Nanorod Photothermal Therapy. J Am Chem Soc 138:15434-15442

Alwarawrah Y, Hughes P, Loiselle D, Carlson DA, Darr DB, Jordan JL, Xiong J, Hunter LM, Dubois LG, Thompson JW, Kulkarni MM, Ratcliff AN, Kwiek JJ, Haystead TA (2016) Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol 23:678-688

Arias M, Chevallier OP, Graham SF, Gasull-Gimenez A, Fodey T, Cooper KM, Crooks SR, Danaher M, Elliott CT (2016) Metabolomics reveals novel biomarkers of illegal 5-nitromimidazole treatment in pigs. Further evidence of drug toxicity uncovered. Food Chem 199:876-884

Black C, Haughey SA, Chevallier OP, Galvin-King P, Elliott CT (2016) A comprehensive strategy to detect the fraudulent adulteration of herbs: The oregano approach. Food Chem 210:551-557

Blaise BJ, Correia G, Tin A, Young JH, Vergnaud AC, Lewis M, Pearce JT, Elliott P, Nicholson JK, Holmes E, Ebbels TM (2016) Power Analysis and Sample Size Determination in Metabolic Phenotyping. Anal Chem 88:5179-5188

Brown JA, Codreanu SG, Shi M, Sherrod SD, Markov DA, Neely MD, Britt CM, Hoilett OS, Reiserer RS, Samson PC, McCawley LJ, Webb DJ, Bowman AB, McLean JA, Wikswo JP (2016) Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit. J Neuroinflammation 13:306

Cao J, Li M, Chen J, Liu P, Li Z (2016) Effects of MeJA on Arabidopsis metabolome under endogenous JA deficiency. Sci Rep 6:37674

Carrizo D, Chevallier OP, Woodside JV, Brennan SF, Cantwell MM, Cuskelly G, Elliott CT (2016) Untargeted metabolomic analysis of human serum samples associated with exposure levels of Persistent organic pollutants indicate important perturbations in Sphingolipids and Glycerophospholipids levels. Chemosphere 168:731-738

Chen H, Cao G, Chen DQ, Wang M, Vaziri ND, Zhang ZH, Mao JR, Bai X, Zhao YY (2016) Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression. Redox Biol 10:168-178

Chen WW, Freinkman E, Wang T, Birsoy K, Sabatini DM (2016) Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism. Cell 166:1324-1337 e1311

Chen YX, Zhang XJ, Huang J, Zhou SJ, Liu F, Jiang LL, Chen M, Jian-Bo W, Yang DZ (2016) UHPLC/Q-TOFMS-based plasma metabolomics of polycystic ovary syndrome patients with and without insulin resistance. J Pharm Biomed Anal 121:141-150

Chen Z, Xu X, Zhang J, Liu Y, Li L, Wang W, Xu H, Jiang W, Wang Y (2016) Application of LC-MS-Based Global Metabolomic Profiling Methods to Human Mental Fatigue. Anal Chem 88:11293-11296

Chu H, Zhang A, Han Y, Lu S, Kong L, Han J, Liu Z, Sun H, Wang X (2016) Metabolomics approach to explore the effects of Kai-Xin-San on Alzheimer's disease using UPLC/ESI-Q-TOF mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 1015-1016:50-61

Cowan E, Kumar P, Burch KJ, Grieve DJ, Green BD, Graham SF (2016) Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics. Metabolomics 12:124

Dhungana S, Carlson JE, Pathmasiri W, McRitchie S, Davis M, Sumner S, Appt SE (2016) Impact of a western diet on the ovarian and serum metabolome. Maturitas 92:134-142

Fang H, Zhang A, Yu J, Wang L, Liu C, Zhou X, Sun H, Song Q, Wang X (2016) Insight into the metabolic mechanism of scoparone on biomarkers for inhibiting Yanghuang syndrome. Sci Rep 6:37519

Gray N, Adesina-Georgiadis K, Chekmeneva E, Plumb RS, Wilson ID, Nicholson JK (2016) Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies. Anal Chem 88:5742-5751

Huang W, Robert CA, Herve MR, Hu L, Bont Z, Erb M (2016) A mechanism for sequence specificity in plant-mediated interactions between herbivores. New Phytol 214:169-179

Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z (2016) A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med 22:421-426

Jones JW, Carter CL, Li F, Yu J, Pierzchalski K, Jackson IL, Vujaskovic Z, Kane MA (2016) Ultraperformance convergence chromatography-high resolution tandem mass spectrometry for lipid biomarker profiling and identification. Biomed Chromatogr (In press)

Kaakoush NO, Pickford R, Jaffe A, Ooi CY (2016) Is there a role for stool metabolomics in cystic fibrosis? Pediatr Int 58:808-811

Kim MS, Jin JS, Kwak YS, Hwang GS (2016) Metabolic Response of Strawberry (Fragaria x ananassa) Leaves Exposed to the Angular Leaf Spot Bacterium (Xanthomonas fragariae). J Agric Food Chem 64:1889-1898

Kim W, Peever TL, Park JJ, Park CM, Gang DR, Xian M, Davidson JA, Infantino A, Kaiser WJ, Chen W (2016) Use of metabolomics for the chemotaxonomy of legume-associated Ascochyta and allied genera. Sci Rep 6:20192

Kong Z, Li M, An J, Chen J, Bao Y, Francis F, Dai X (2016) The fungicide triadimefon affects beer flavor and composition by influencing Saccharomyces cerevisiae metabolism. Sci Rep 6:33552

Lai CJ, Zha L, Liu DH, Kang L, Ma X, Zhan ZL, Nan TG, Yang J, Li F, Yuan Y, Huang LQ (2016) Global profiling and rapid matching of natural products using diagnostic product ion network and in silico analogue database: Gastrodia elata as a case study. J Chromatogr A 1456:187-195

Laiakis EC, Pannkuk EL, Diaz-Rubio ME, Wang YW, Mak TD, Simbulan-Rosenthal CM, Brenner DJ, Fornace AJ, Jr. (2016) Implications of genotypic differences in the generation of a urinary metabolomics radiation signature. Mutat Res 788:41-49

Lesche D, Geyer R, Lienhard D, Nakas CT, Diserens G, Vermathen P, Leichtle AB (2016) Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome. Metabolomics 12:159

Lewis MR, Pearce JT, Spagou K, Green M, Dona AC, Yuen AH, David M, Berry DJ, Chappell K, Horneffer-van der Sluis V, Shaw R, Lovestone S, Elliott P, Shockcor J, Lindon JC, Cloarec O, Takats Z, Holmes E, Nicholson JK (2016) Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping. Anal Chem 88:9004-9013

McIlroy GD, Tammireddy SR, Maskrey BH, Grant L, Doherty MK, Watson DG, Delibegovic M, Whitfield PD, Mody N (2016) Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol 100:86-97

Mnich E, Vanholme R, Oyarce P, Liu S, Lu F, Goeminne G, Jorgensen B, Motawie MS, Boerjan W, Ralph J, Ulvskov P, Moller BL, Bjarnholt N, Harholt J (2016) Degradation of lignin beta-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6. Plant Biotechnol J 15:581-593

Nakabayashi R, Sawada Y, Aoyagi M, Yamada Y, Hirai MY, Sakurai T, Kamoi T, Rowan DD, Saito K (2016) Chemical Assignment of Structural Isomers of Sulfur-Containing Metabolites in Garlic by Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry. J Nutr 146:397S-402S

Paglia G, Stocchero M, Cacciatore S, Lai S, Angel P, Alam MT, Keller M, Ralser M, Astarita G (2016) Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism. J Proteome Res 15:608-618

Pirhaji L, Milani P, Leidl M, Curran T, Avila-Pacheco J, Clish CB, White FM, Saghatelian A, Fraenkel E (2016) Revealing disease-associated pathways by network integration of untargeted metabolomics. Nat Methods 13:770-776

Plucinska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield PD, Doherty MK, Mingarelli M, Welch A, Riedel G, Delibegovic M, Platt B (2016) Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia 59:1513-1523

Prudent M, Stauber F, Rapin A, Hallen S, Pham N, Abonnenc M, Marvin L, Rochat B, Tissot JD, Lion N (2016) Small-Scale Perfusion Bioreactor of Red Blood Cells for Dynamic Studies of Cellular Pathways: Proof-of-Concept. Front Mol Biosci 3:11

Rusilowicz M, Dickinson M, Charlton A, O'Keefe S, Wilson J (2016) A batch correction method for liquid chromatography-mass spectrometry data that does not depend on quality control samples. Metabolomics 12:56

Saigusa D, Okamura Y, Motoike IN, Katoh Y, Kurosawa Y, Saijyo R, Koshiba S, Yasuda J, Motohashi H, Sugawara J, Tanabe O, Kinoshita K, Yamamoto M (2016) Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery. PLoS One 11:e0160555

Salem MA, Juppner J, Bajdzienko K, Giavalisco P (2016) Protocol: a fast, comprehensive and reproducible one-step extraction method for the rapid preparation of polar and semi-polar metabolites, lipids, proteins, starch and cell wall polymers from a single sample. Plant Methods 12:45

Schmidt R, Ostorhazi E, Wende E, Knappe D, Hoffmann R (2016) Pharmacokinetics and in vivo efficacy of optimized oncocin derivatives. J Antimicrob Chemother 71:1003-1011

Shahaf N, Rogachev I, Heinig U, Meir S, Malitsky S, Battat M, Wyner H, Zheng S, Wehrens R, Aharoni A (2016) The WEIZMASS spectral library for high-confidence metabolite identification. Nat Commun 7:12423

Shen S, Weng R, Li L, Xu X, Bai Y, Liu H (2016) Metabolomic Analysis of Mouse Embryonic Fibroblast Cells in Response to Autophagy Induced by Acute Starvation. Sci Rep 6:34075

Shi H, Hu L, Chen S, Bao W, Yang S, Zhao X, Sun C (2016) Metabolomics analysis of urine from rats administered with long-term, low-dose acrylamide by ultra-performance liquid chromatography-mass spectrometry. Xenobiotica:1-11

Steenackers W, Cesarino I, Klima P, Quareshy M, Vanholme R, Corneillie S, Kumpf RP, Van de Wouwer D, Ljung K, Goeminne G, Novak O, Zazimalova E, Napier R, Boerjan W, Vanholme B (2016) The Allelochemical MDCA Inhibits Lignification and Affects Auxin Homeostasis. Plant Physiol 172:874-888

Vaughan D, Brogioli M, Maier T, White A, Waldron S, Rittweger J, Toigo M, Wettstein J, Laczko E, Fluck M (2016) The Angiotensin Converting Enzyme Insertion/Deletion Polymorphism Modifies Exercise-Induced Muscle Metabolism. PLoS One 11:e0149046

Wali S, Gupta R, Yu JJ, Mfuh A, Gao X, Guentzel MN, Chambers JP, Abu Bakar S, Zhong G, Arulanandam BP (2016) Guinea pig genital tract lipidome reveals in vivo and in vitro regulation of phosphatidylcholine 16:0/18:1 and contribution to Chlamydia trachomatis serovar D infectivity. Metabolomics 12 (In press)

Walton A, Stes E, Goeminne G, Braem L, Vuylsteke M, Matthys C, De Cuyper C, Staes A, Vandenbussche J, Boyer FD, Vanholme R, Fromentin J, Boerjan W, Gevaert K, Goormachtig S (2016) The Response of the Root Proteome to the Synthetic Strigolactone GR24 in Arabidopsis. Mol Cell Proteomics 15:2744-2755

Wang J, Qi P, Hou J, Shen Y, Yang M, Bi Q, Deng Y, Shi X, Feng R, Feng Z, Wu W, Guo D (2016) The profiling of the metabolites of hirsutine in rat by ultra-high performance liquid chromatography coupled with linear ion trap Orbitrap mass spectrometry: An improved strategy for the systematic screening and identification of metabolites in multi-samples in vivo. J Pharm Biomed Anal 134:149-157

Yang Z, Hou JJ, Qi P, Yang M, Yan BP, Bi QR, Feng RH, Yang WZ, Wu WY, Guo DA (2016) Colon-derived uremic biomarkers induced by the acute toxicity of Kansui radix: A metabolomics study of rat plasma and intestinal contents by UPLC-QTOF-MS(E). J Chromatogr B Analyt Technol Biomed Life Sci 1026:193-203

Zhang A, Liu Q, Zhao H, Zhou X, Sun H, Nan Y, Zou S, Ma CW, Wang X (2016) Phenotypic characterization of nanshi oral liquid alters metabolic signatures during disease prevention. Sci Rep 6:19333

Zhang J, Yang W, Li S, Yao S, Qi P, Yang Z, Feng Z, Hou J, Cai L, Yang M, Wu W, Guo DA (2016) An intelligentized strategy for endogenous small molecules characterization and quality evaluation of earthworm from two geographic origins by ultra-high performance HILIC/QTOF MS(E) and Progenesis QI. Anal Bioanal Chem 408:3881-3890

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2015

Ashraf-Khorassani M, Yang J, Rainville P, Jones MD, Fountain KJ, Isaac G, Taylor LT (2015) Ultrahigh performance supercritical fluid chromatography of lipophilic compounds with application to synthetic and commercial biodiesel. J Chromatogr B Analyt Technol Biomed Life Sci 983-984:94-100

Avin-Wittenberg T, Bajdzienko K, Wittenberg G, Alseekh S, Tohge T, Bock R, Giavalisco P, Fernie AR (2015) Global Analysis of the Role of Autophagy in Cellular Metabolism and Energy Homeostasis in Arabidopsis Seedlings under Carbon Starvation. Plant Cell 27:306-322

Boulard C, Bardet M, Chardot T, Dubreucq B, Gromova M, Guillermo A, Miquel M, Nesi N, Yen-Nicolay S, Jolivet P (2015) The structural organization of seed oil bodies could explain the contrasted oil extractability observed in two rapeseed genotypes. Planta 242:53-68

Burch TC, Isaac G, Booher CL, Rhim JS, Rainville P, Langridge J, Baker A, Nyalwidhe JO (2015) Comparative Metabolomic and Lipidomic Analysis of Phenotype Stratified Prostate Cells. PLoS One 10:e0134206

Chetwynd AJ, Abdul-Sada A, Holt SG, Hill EM (2015) Use of a pre-analysis osmolality normalisation method to correct for variable urine concentrations and for improved metabolomic analyses. J Chromatogr A (In press)

Chevallier OP, Graham SF, Alonso E, Duffy C, Silke J, Campbell K, Botana LM, Elliott CT (2015) New insights into the causes of human illness due to consumption of azaspiracid contaminated shellfish. Sci Rep 5:9818

Dai W, Qi D, Yang T, Lv H, Guo L, Zhang Y, Zhu Y, Peng Q, Xie D, Tan J, Lin Z (2015) Nontargeted Analysis Using Ultraperformance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry Uncovers the Effects of Harvest Season on the Metabolites and Taste Quality of Tea (Camellia sinensis L.). J Agric Food Chem 63:9869-9878

Deutsch EW, Mendoza L, Shteynberg D, Slagel J, Sun Z, Moritz RL (2015) Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics. Proteomics Clin Appl 9:745-754 (in press)

Graham SF, Chevallier OP, Elliott CT, Holscher C, Johnston J, McGuinness B, Kehoe PG, Passmore AP, Green BD (2015) Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease. PLoS One 10:e0119452

Gray N, Lewis MR, Plumb RS, Wilson ID, Nicholson JK (2015) High-Throughput Microbore UPLC-MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies. J Proteome Res 14:2714-2721

Haoula Z, Ravipati S, Stekel DJ, Ortori CA, Hodgman C, Daykin C, Raine-Fenning N, Barrett DA, Atiomo W (2015) Lipidomic analysis of plasma samples from women with polycystic ovary syndrome. Metabolomics 11:657-666

Holcapek M, Cervena B, Cifkova E, Lisa M, Chagovets V, Vostalova J, Bancirova M, Galuszka J, Hill M (2015) Lipidomic analysis of plasma, erythrocytes and lipoprotein fractions of cardiovascular disease patients using UHPLC/MS, MALDI-MS and multivariate data analysis. J Chromatogr B Analyt Technol Biomed Life Sci 990:52-63

Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM (2015) SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature 520:363-367

Lin L, Lin H, Zhang M, Ni B, Yin X, Qu C, Ni J (2015) A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. J Hazard Mater 299:249-259

Liu F, Bai X, Ding RB, Hu YJ, Su H, Wan JB (2015) UPLC/Q-TOFMS-Based Metabolomics Studies on the Protective Effect of Panax notoginseng Saponins on Alcoholic Liver Injury. Am J Chin Med 43:695-714

Liu H, Zhang L, Zhao B, Zhang Z, Qin L, Zhang Q, Wang Q, Lu Z, Gao X (2015) Hypothalamus metabolomic profiling to elucidate the tissue-targeted biochemical basis of febrile response in yeast-induced pyrexia rats. Chem Biol Interact 231:61-70

Maldini M, Natella F, Baima S, Morelli G, Scaccini C, Langridge J, Astarita G (2015) Untargeted Metabolomics Reveals Predominant Alterations in Lipid Metabolism Following Light Exposure in Broccoli Sprouts. Int J Mol Sci 16:13678-13691

McIlroy GD, Tammireddy SR, Maskrey BH, Grant L, Doherty MK, Watson DG, Delibegovic M, Whitfield PD, Mody N (2015) Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol (In press)

Mertens J, Pollier J, Vanden Bossche R, Lopez-Vidriero I, Franco-Zorrilla JM, Goossens A (2015) The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula. Plant Physiol 170:194-210

Milner JJ, Rebeles J, Dhungana S, Stewart DA, Sumner SC, Meyers MH, Mancuso P, Beck MA (2015) Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice. J Immunol 194:4846-4859

Mulek M, Fekete A, Wiest J, Holzgrabe U, Mueller MJ, Hogger P (2015) Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach. J Pharm Biomed Anal 114:71-81

Nakabayashi R, Yang Z, Nishizawa T, Mori T, Saito K (2015) Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis. J Nat Prod 78:1179-1183

Neubauer C, Dalleska NF, Cowley ES, Shikuma NJ, Wu CH, Sessions AL, Newman DK (2015) Lipid remodeling in Rhodopseudomonas palustris TIE-1 upon loss of hopanoids and hopanoid methylation. Geobiology 13:443-453

Pacini T, Fu W, Gudmundsson S, Chiaravalle AE, Brynjolfson S, Palsson BO, Astarita G, Paglia G (2015) Multidimensional analytical approach based on UHPLC-UV-ion mobility-MS for the screening of natural pigments. Anal Chem 87:2593-2599

Passos-Castilho AM, Carvalho VM, Cardozo KH, Kikuchi L, Chagas AL, Gomes-Gouvea MS, Malta F, de Seixas-Santos Nastri AC, Pinho JR, Carrilho FJ, Granato CF (2015) Serum lipidomic profiling as a useful tool for screening potential biomarkers of hepatitis B-related hepatocellular carcinoma by ultraperformance liquid chromatography-mass spectrometry. BMC Cancer 15:985

Stark TD, Losch S, Wakamatsu J, Balemba OB, Frank O, Hofmann T (2015) UPLC-ESI-TOF MS-Based Metabolite Profiling of the Antioxidative Food Supplement Garcinia buchananii. J Agric Food Chem 63:7169-7179

Stewart CJ, Nelson A, Treumann A, Skeath T, Cummings SP, Embleton ND, Berrington JE (2015) Metabolomic and proteomic analysis of serum from preterm infants with necrotising entercolitis and late-onset sepsis. Pediatr Res (In press)

Tonoli D, Furstenberger C, Boccard J, Hochstrasser D, Jeanneret F, Odermatt A, Rudaz S (2015) Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells. Chem Res Toxicol 28:955-966

Wang_XK (2015) Identification of particulate organosulfates in three megacities at the middle and lower reaches of the Yangtze River. Atmos Chem Phys Discuss 15:21415–21448

Watschinger K, Keller MA, McNeill E, Alam MT, Lai S, Sailer S, Rauch V, Patel J, Hermetter A, Golderer G, Geley S, Werner-Felmayer G, Plumb RS, Astarita G, Ralser M, Channon KM, Werner ER (2015) Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome. Proc Natl Acad Sci U S A 112:2431-2436

Yang Z, Hou JJ, Qi P, Yang M, Yan BP, Bi QR, Feng RH, Yang WZ, Wu WY, Guo DA (2015) Colon-derived uremic biomarkers induced by the acute toxicity of Kansui radix: A metabolomics study of rat plasma and intestinal contents by UPLC-QTOF-MS. J Chromatogr B Analyt Technol Biomed Life Sci (in press)

Zhang ZH, Wei F, Vaziri ND, Cheng XL, Bai X, Lin RC, Zhao YY (2015) Metabolomics insights into chronic kidney disease and modulatory effect of rhubarb against tubulointerstitial fibrosis. Sci Rep 5:14472

Zhao YY, Wang HL, Cheng XL, Wei F, Bai X, Lin RC, Vaziri ND (2015) Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis, and Nrf2 dysfunction in aristolochic acid-induced nephropathy. Sci Rep 5:12936

Zhao Y, Liu T, Luo J, Zhang Q, Xu S, Han C, Xu J, Chen M, Chen Y, Kong L (2015) Integration of a Decrescent Transcriptome and Metabolomics Dataset of Peucedanum praeruptorum to Investigate the CYP450 and MDR Genes Involved in Coumarins Biosynthesis and Transport. Front Plant Sci 6:996

Zhou T, Wang M, Cheng H, Cui C, Su S, Xu P, Xue M (2015) UPLC-HRMS based metabolomics reveals the sphingolipids with long fatty chains and olefinic bonds up-regulated in metabolic pathway for hypoxia preconditioning. Chem Biol Interact 242:145-152

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2014

Astarita G, McKenzie JH, Wang B, Strassburg K, Doneanu A, Johnson J, Baker A, Hankemeier T, Murphy J, Vreeken RJ, Langridge J, Kang JX (2014) A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice. PLoS One 9:e96221

Avanesov AS, Ma S, Pierce KA, Yim SH, Lee BC, Clish CB, Gladyshev VN (2014) Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation. Elife 3:e02077

Damen CW, Isaac G, Langridge J, Hankemeier T, Vreeken RJ (2014) Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection. J Lipid Res 55:1772-1783

Laiakis EC, Strassburg K, Bogumil R, Lai S, Vreeken RJ, Hankemeier T, Langridge J, Plumb RS, Fornace AJ, Jr., Astarita G (2014) Metabolic phenotyping reveals a lipid mediator response to ionizing radiation. J Proteome Res 13:4143-4154

Paglia G, Angel PM, Williams JP, Richardson K, Olivos HJ, Thompson JW, Menikarachchi LC, Lai S, Walsh C, Moseley MA, Plumb RS, Grant DF, Palsson BO, Langridge JI, Geromanos SJ, Astarita G (2014) Ion-Mobility-Derived Collision Cross Section as an Additional Measure for Lipid Fingerprinting and Identification. Anal Chem

Paglia G, Williams JP, Menikarachchi L, Thompson JW, Tyldesley-Worster R, Halldorsson S, Rolfsson O, Moseley A, Grant D, Langridge J, Palsson BO, Astarita G (2014) Ion mobility derived collision cross sections to support metabolomics applications. Anal Chem 86:3985-3993

Sedic M, Gethings LA, Vissers JP, Shockcor JP, McDonald S, Vasieva O, Lemac M, Langridge JI, Batinic D, Pavelic SK (2014) Label-free mass spectrometric profiling of urinary proteins and metabolites from paediatric idiopathic nephrotic syndrome. Biochem Biophys Res Commun 452:21-26

Sundin L, Vanholme R, Geerinck J, Goeminne G, Hofer R, Kim H, Ralph J, Boerjan W (2014) Mutation of the Inducible ARABIDOPSIS THALIANA CYTOCHROME P450 REDUCTASE2 Alters Lignin Composition and Improves Saccharification. Plant Physiol 166:1956-1971

Van Acker R, Leple JC, Aerts D, Storme V, Goeminne G, Ivens B, Legee F, Lapierre C, Piens K, Van Montagu MC, Santoro N, Foster CE, Ralph J, Soetaert W, Pilate G, Boerjan W (2014) Improved saccharification and ethanol yield from field-grown transgenic poplar deficient in cinnamoyl-CoA reductase. Proc Natl Acad Sci U S A 111:845-850

Zhang A, Zhou X, Zhao H, Guan Y, Zhou S, Yan GL, Ma Z, Liu Q, Wang X (2014) Rapidly improved determination of metabolites from biological data sets using the high-efficient TransOmics tool. Mol Biosyst 10:2160-2165